Science
Mechanism of Action
POLYGLYCERYL-4 DIISOSTEARATE/POLYHYDROXYSTEARATE/SEBACATE operates by reducing surface tension, enabling the formation of stable emulsions between normally immiscible liquids like oils and water. As a key emulsion stabilizer, it significantly enhances product longevity and consistency. Beyond its emulsifying role, it acts as a humectant, drawing moisture into the stratum corneum for improved hydration and a softened skin texture, while also offering a degree of skin protection.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 Guinea pig studies confirmed this ingredient is not a sensitizer. Clinical evaluations further support its excellent tolerability, showing rare instances of allergic reactions or irritation, making it suitable even for sensitive skin. Patent data indicates advantageous use in cosmetic or dermatological preparations at concentrations of 0.0001% to 15% by weight, with a particularly preferred range of 0.05% to 2.5% for optimal performance.
Transparency
Dusting Analysis
This ingredient, which is a liquid emulsifier, has been noted as potentially feeding fungal acne. Formulators should consider this when creating products for individuals prone to malassezia-related skin conditions.
The Formula
Formulation
Stability
This liquid emulsifier is highly valued for its ability to create stable water-in-oil emulsions, even with a remarkably low oil phase (down to 18-20%). It offers robust formulation stability, extends product shelf life, and demonstrates excellent compatibility with high concentrations of silicone oils. Its liquid nature also facilitates cold-processing techniques for water-in-oil formulations. It can function effectively as a primary or co-emulsifier and is often integrated into formulations utilizing vegetable oils.
Synergies
- High compatibility with silicone oils
- Effective in formulations based on vegetable oils
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Panel has deemed this ingredient safe for use in cosmetics when formulated to prevent irritation. It is widely recognized as free of common irritants and allergens by platforms like SkinSAFE, earning 'SAFE' ratings across various categories including Teen, Lip, Baby, and Eyelid. European Cosmetics Regulation also permits its safe use under stringent guidelines.
Your Skin
Skin Compatibility
Our Assessment
Verdict
POLYGLYCERYL-4 DIISOSTEARATE/POLYHYDROXYSTEARATE/SEBACATE is a highly versatile and generally well-tolerated emulsifier and humectant, enhancing formulation stability and skin hydration, though formulators should note its potential to feed fungal acne.
Related
Similar Ingredients
Finding similar ingredients…
References
Sources
- cir-safety.org ↗
- sincereskincare.com ↗
- ask-naos.ie ↗
- incibeauty.com ↗
- skinsort.com ↗
- hc-sc.gc.ca ↗
- cosmileeurope.eu ↗
- ci.guide ↗
- bentoncosmetics.com ↗
- thegoodscentscompany.com ↗
- tiiips.com ↗
- skinsafeproducts.com ↗
- google.com ↗
- beautydecoded.com ↗