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POLYGLYCERYL-3 TRIISOSTEARATE.

Valuable CAS 66082-43-7 / SKIN CONDITIONING - EMOLLIENT, SURFACTANT - EMULSIFYING

Polyglyceryl-3 Triisostearate is a versatile polyglyceryl fatty acid ester primarily functioning as an emulsifier, facilitating the stable blending of immiscible oil and water phases in formulations. Beyond its emulsifying capabilities, it also acts as a skin-conditioning agent and surfactant, enhancing formula spreadability.

Summary

Emulsifier Skin-conditioning agent Surfactant

Science

Mechanism of Action

This ingredient operates by significantly reducing the interfacial tension between diverse formulation components, allowing for the creation of stable emulsions where oil and water can coexist harmoniously. As a polyglyceryl fatty acid ester, it also contributes to skin conditioning, offering emollient properties, and acts as a surfactant to improve the dispersion and uniform application of products on the skin.

Research

Clinical Evidence

Insufficient-data confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

While specific data for Polyglyceryl-3 Triisostearate is limited, a closely related compound, Polyglyceryl-3 Diisostearate, demonstrates robust stability across a wide pH spectrum, effectively maintaining its emulsifying properties in both acidic and alkaline environments.

Conflicts

  • Retinol (based on Polyglyceryl-3 Diisostearate)
  • Salicylic Acid (based on Polyglyceryl-3 Diisostearate)
  • Glycolic Acid (based on Polyglyceryl-3 Diisostearate)

Safety

Safety Profile

CIR Status
Safe as used
Max tested
40%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has deemed polyglyceryl fatty acid esters, including closely related compounds like Polyglyceryl-2 Triisostearate, safe for use in cosmetics. This safety assessment is contingent on formulations being non-irritating. The highest reported concentration for a related compound in leave-on products is 40%. No specific SCCS opinion or FDA status for Polyglyceryl-3 Triisostearate itself was identified.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Polyglyceryl-3 Triisostearate is a valuable functional ingredient, essential for creating stable and aesthetically pleasing emulsions across a broad range of skincare and cosmetic formulations.

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