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POLYGLYCERYL-3 PALMITATE.

Valuable CAS 143710-24-1 / SKIN CONDITIONING - EMOLLIENT, SURFACTANT - EMULSIFYING

Polyglyceryl-3 Palmitate is a versatile ester functioning primarily as an emulsifier to stabilize oil-in-water mixtures in cosmetic formulations. Beyond its structural role, it provides significant skin-conditioning and emollient benefits, enhancing skin hydration and smoothness. This ingredient supports skin barrier function, contributing to reduced transepidermal water loss.

Emulsifier Emollient Skin-Conditioning Agent Humectant Surfactant

Science

This ingredient effectively stabilizes emulsions by facilitating the uniform dispersion of immiscible oil and water phases. On the skin, it forms a light, protective film that softens and smooths the surface, actively preventing moisture loss and reinforcing the skin barrier. Its molecular structure combines the humectant properties of polyglycerin-3 with the emollient characteristics of palmitic acid, delivering a dual benefit of hydration and skin conditioning. Additionally, it possesses surfactant qualities, enabling gentle foaming and cleansing action.


Research

Low confidence
Effective range 1–5%
Optimal

5%


Transparency

Not commonly dusted

The Formula

Solubility
Both
Optimal pH 4 – 8
0 7 14

Stability

Polyglyceryl-3 Palmitate demonstrates excellent stability within a pH range of 4.0 to 8.0. Its emulsification performance is particularly robust under acidic conditions. Formulators should avoid exposing the ingredient to temperatures above 80°C during the mixing process to maintain its integrity.

Conflicts

  • Accelerated hydrolysis by strong bases or acids due to its ester linkage
  • Degradation by lipases

Safety

CIR Status
Safe as used
Max tested
5%
Sensitization risk Low

The CIR Expert Panel has concluded that Polyglyceryl-3 Palmitate is safe for use in cosmetic formulations, alongside 273 other polyglyceryl fatty acid esters. This assessment is based on current usage practices and concentrations, provided the final product is formulated to be non-irritating. Typical usage rates range from 1% to 5%.


Your Skin

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

Polyglyceryl-3 Palmitate is a valuable ingredient, effectively blending emulsifying capabilities with significant skin-conditioning and emollient benefits for dry, sensitive, and normal skin types, at concentrations up to 5%.


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