Science
Mechanism of Action
This ingredient operates as both an emulsifier and surfactant, effectively reducing interfacial tension to allow immiscible liquids like oil and water to combine into stable emulsions. On the skin, it acts as an emollient by bridging microscopic gaps between skin cells, creating a perceptibly smoother surface. It forms a protective barrier that actively prevents moisture loss, shields against environmental aggressors, and enhances the overall integrity of the skin's barrier function, thereby promoting soft, supple, and hydrated skin.
Research
Clinical Evidence
Low confidenceN/A
Key findings
- 01 Found not to be irritating in a 24-hour semi-occlusive patch test conducted on 50 subjects.
- 02 Polyglycerol esters generally do not induce adverse effects.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Polyglyceryl-2 Sesquiisostearate exhibits high chemical stability and is suitable for cold-process emulsification. Its ester linkage can undergo accelerated hydrolysis in the presence of strong acids or bases, and it is also susceptible to degradation by lipases.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel concluded that polyglyceryl fatty acid esters, including Polyglyceryl-2 Sesquiisostearate, are safe for use in cosmetics when formulated to be non-irritating. Clinical testing confirmed that undiluted Polyglyceryl-2 Sesquiisostearate caused no irritation in a 24-hour patch test.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Polyglyceryl-2 Sesquiisostearate is a valuable, well-tolerated ingredient that effectively stabilizes emulsions while simultaneously delivering significant skin barrier support and moisturization benefits across various skin types.
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