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POLYGLYCERIN-40.

Valuable CAS 25618-55-7 / ANTIMICROBIAL, HUMECTANT

Polyglycerin-40 is a high molecular weight polyglycerin derivative, primarily functioning as a potent humectant that draws and retains moisture in the skin for prolonged hydration. It also acts as an effective emulsifier and stabilizer, contributing to robust product formulations.

humectant emulsifier skin-conditioning agent

Science

As a polyglycerin, Polyglycerin-40 operates as a humectant by attracting and binding water molecules, thereby enhancing skin hydration. Its larger molecular structure, relative to glycerin, is hypothesized to facilitate slower skin penetration, resulting in extended moisturizing benefits. This action supports the skin's natural moisture balance, mitigating dryness and flaking, and promoting a supple, elastic, and plump complexion. Additionally, it serves as an emulsifier and stabilizer in formulations, aiding in the creation of stable and uniform product textures, while also contributing to the maintenance of the skin's barrier function.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 3.5 – 8.5
0 7 14

Stability

Polyglycerols maintain stability across a broad pH range of 3.5 to 8.5, enabling their use in formulations designed to be stable under varying thermal conditions, including heat and freeze cycles. Their versatility ensures compatibility with a diverse array of cosmetic ingredients, often enhancing emulsion stability and assisting in achieving desired viscosity without relying solely on additional thickening agents.


Safety

CIR Status
Safe as used
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has deemed various polyglycerins, including those with lower polymerization degrees (e.g., Diglycerin, Polyglycerin-3, Polyglycerin-6, Polyglycerin-10), 'safe in cosmetics in the present practices of use and concentrations.' They consider polyglycerins as glycerin polymers and utilize glycerin data for safety assessments, noting minimal skin absorption and no dermal irritation or sensitization. While Polyglycerin-40 was not explicitly listed, the overall safety profile for polyglycerins suggests a similar benign nature. Furthermore, the FDA permits polyglycerol esters of fatty acids (up to decaglycerol esters) in food, and a GRAS Notice supports the safety of polyglycerol fatty acid esters with a degree of polymerization up to 40 for food use.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Valuable

Polyglycerin-40 is a valuable ingredient, offering multi-faceted benefits as a long-lasting humectant, effective emulsifier, and formulation stabilizer, with a robust safety profile supported by broader polyglycerin assessments.


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