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POLYGLYCERIN-3.

Valuable CAS 56090-54-1 / HUMECTANT

Polyglycerin-3 is a multi-functional ingredient serving as a powerful humectant to deeply hydrate the skin, and an effective emulsifier for stable formulations. Its larger molecular structure compared to glycerin ensures prolonged moisture retention in the epidermis, enhancing skin barrier function and overall skin health.

Moisturizer/Humectant Emulsifier

Science

This humectant draws and binds water within the stratum corneum, supporting optimal moisture levels. Its increased molecular size facilitates slower penetration, leading to extended hydration within the upper skin layers. Polyglycerin-3 actively contributes to improving skin barrier integrity, mechanical properties, and may mitigate lipid phase transitions in the stratum corneum, offering protection against irritants. In-vitro research additionally indicates potential anti-inflammatory benefits.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Polyglycerin-3 acts as a robust stabilizer, improving product consistency and ensuring uniform distribution of active compounds. It functions as an effective surfactant and emulsifier, capable of bridging immiscible oil and water phases to create stable water-in-oil (W/O) and oil-in-water (O/W) emulsions. It demonstrates high compatibility across a diverse range of cosmetic ingredients, including active compounds and pigments.

Synergies

  • Broad compatibility with cosmetic ingredients

Safety

CIR Status
Safe as used
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel concluded Polyglycerin-3 is safe for use in cosmetic formulations. As of 2023, it is reported in 221 cosmetic products. While related ingredients like Diglycerin have been noted at concentrations up to 28% in specific product types, a definitive maximum concentration for Polyglycerin-3 itself for dermal exposure is not explicitly stated. It is recognized as safe by European Cosmetics Regulation and classified as low concern by the EPA Safer Choice program.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Polyglycerin-3 is a valuable ingredient, providing long-lasting hydration, supporting skin barrier health, and enhancing formulation stability with its excellent safety and compatibility profile.


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