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POLYGLUCURONIC ACID.

Valuable CAS 36655-86-4 / SKIN CONDITIONING

Polyglucuronic acid is a sophisticated polysaccharide that intensely moisturizes and conditions the skin by attracting and binding water molecules. It actively supports the skin's natural repair processes, visibly diminishing the appearance of fine lines and wrinkles while forming a protective, smoothing film to prevent dehydration.

Skin Moisturizer Anti-aging Agent Humectant Film-forming Agent Skin Conditioning Skin Repair

Science

This ingredient functions as a potent humectant, efficiently attracting and attaching water molecules to the stratum corneum, thereby enhancing skin hydration. It actively stimulates the skin's intrinsic repair mechanisms and acts as a film-forming agent, creating a smooth surface that reduces transepidermal water loss. Furthermore, it serves as a critical precursor for the synthesis of key dermal components like laminin-5 and hyaluronic acid, augmenting the skin's capacity for sustained water retention.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 1 – 9
0 7 14

Stability

Polyglucuronic acid (specifically its sodium salt, (1→3)-β-polyglucuronic acid Na salt) demonstrates robust stability in aqueous solutions across a broad pH range of 1 to 9, maintaining integrity without depolymerization for up to 128 hours at room temperature. Minor depolymerization was observed only at more extreme alkaline conditions, specifically pH 11 and 13.


Safety

CIR Status
Not reviewed
Sensitization risk Low

Generally recognized as safe for cosmetic applications, Polyglucuronic acid exhibits excellent skin tolerability. It is rated 'LOW' by EWG Skin Deep for concerns including cancer, allergies, immunotoxicity, developmental and reproductive toxicity, and is absent from EWG's Restricted or Unacceptable Lists. The Good Scents Company further corroborates its safety profile, indicating no GHS hazard or precautionary statements.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Valuable

Polyglucuronic acid is a valuable hydrating and anti-aging ingredient, demonstrating broad skin compatibility and a robust safety profile, making it suitable for enhancing skin moisture and reducing visible signs of aging.


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