Science
Mechanism of Action
Poloxamine 304 operates as a non-ionic surfactant and an amphiphilic block copolymer. Its core mechanism in formulations is to stabilize emulsions, preventing the separation of oil and water phases. This ensures uniform product texture and consistent delivery of active ingredients, while also contributing to gentle cleansing properties when used as a surfactant.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Poloxamine 304 is an amphiphilic compound, exhibiting solubility in both aqueous and various organic solvents, making it suitable for a wide range of formulation types. It can show sensitivity to changes in pH and temperature. While generally stable under standard storage conditions, prolonged exposure to elevated temperatures (e.g., 40°C) over time may lead to degradation, potentially forming acidic byproducts that could alter product pH. It is advisable to store formulations containing Poloxamine 304 away from extreme temperatures and direct sunlight.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has determined that poloxamers, including poloxamines like Poloxamine 304, are safe for use in cosmetics. The safety assessment emphasizes the critical importance of purification processes to maintain levels of impurities such as ethylene oxide, propylene oxide, and 1,4-dioxane below established regulatory thresholds. The FDA also actively monitors 1,4-dioxane levels in cosmetic products to ensure consumer safety.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Poloxamine 304 is a valuable emulsifier and surfactant, integral for achieving stable and consistent cosmetic formulations that ensure optimal product performance.
Related
Similar Ingredients
Finding similar ingredients…
References
Sources