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Moumoujus

POLOXAMINE 1502.

Valuable CAS 11111-34-5 / SURFACTANT - EMULSIFYING

POLOXAMINE 1502 is a precision-engineered amphiphilic polymer that serves as a highly effective surfactant and emulsifying agent in skincare. Its unique structure enables it to stabilize complex formulations while offering gentle cleansing properties suitable for a wide range of skin types.

Summary

Surfactant Emulsifying Cleansing

Science

Mechanism of Action

This ingredient functions as an ethylenediamine tetrakis(propoxylate-block-ethoxylate) tetrol. It is an amphiphilic block polymer, meaning it possesses both hydrophilic (water-attracting polyoxyethylene) and hydrophobic (oil-attracting polyoxypropylene) chains, all anchored to an ethylene-diamine core. This structure allows it to reduce surface tension, effectively emulsifying oil and water phases and facilitating gentle yet thorough cleansing.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 While specific clinical studies detailing effective concentrations for skincare benefits of POLOXAMINE 1502 were not found, it is utilized in personal care compositions that have been clinically evaluated and described with claims such as 'Dermatologically Tested', 'Clinically Tested', 'Clinically Proven', 'Kind to Skin', 'Mild for skin', and 'Safe for Skin', indicating a favorable safety and mildness profile in various formulations.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH 4.5 – 7
0 7 14

Stability

For optimal stability, formulations containing poloxamer gel compositions are preferably adjusted to a pH range between 4.5 and 7.0. Poloxamine and poloxamer complexes have demonstrated instability when exposed to chlorinated organic solvents in the presence of oxygen, air, or water.

Conflicts

  • Chlorinated organic solvents (in the presence of oxygen, air, or water)

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
10%
Sensitization risk Low

POLOXAMINE 1502 is recognized in the EU inventory of cosmetic ingredients as an emulsifier. While a specific CIR safety assessment for this particular poloxamine is not available, related poloxamers are broadly considered non-toxic and non-irritant. Formulations incorporating POLOXAMINE 1502 have successfully passed clinical evaluations, earning approvals such as 'Safe for Skin' and 'Mild for Skin'. Its FDA cosmetic approval status is not readily specified.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

POLOXAMINE 1502 is a valuable emulsifying and cleansing agent, lauded for its broad skin compatibility and demonstrated mildness in various clinically tested personal care formulations.

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