Science
Mechanism of Action
Operating as a non-ionic surfactant, Poloxamer 188 significantly lowers the surface tension of liquids, which is crucial for solubilizing oil and water, thus enhancing cleansing efficiency. It directly facilitates the lift and removal of environmental pollutants and excess sebum from the skin's surface. Furthermore, research indicates its capacity to potentially repair damaged cellular membranes by integrating into the phospholipid bilayer, increasing local lipid packing density. It also exhibits mild humectant and lubricating properties, contributing to skin hydration and preventing product caking, alongside minor antimicrobial action for product preservation.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Poloxamer 188 demonstrates high solubility in water, even at cold temperatures. Should any precipitation or phase separation occur during product development, the application of heat or sonication can effectively resolve it, ensuring uniform dissolution.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has deemed Poloxamer 188 safe for use in cosmetics, citing consistently negative results in dermal irritation and sensitization tests. While specific reproductive and developmental toxicity data are absent, its high molecular weight suggests minimal skin penetration. The FDA also acknowledges its use as an antibacterial agent in OTC skin wound cleansers. It is important to note the potential for trace amounts of 1,4-dioxane, a manufacturing byproduct, which reputable brands control through purification. Environment Canada has raised concerns regarding moderate persistence, bioaccumulation, and low to moderate non-reproductive organ system toxicity.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Poloxamer 188 is a valuable, mild surfactant highly effective in cleansing and emulsifying, suitable for all skin types with a low irritation potential.
Related
Similar Ingredients
Finding similar ingredients…