Science
Mechanism of Action
The extract's rich composition provides antimicrobial, anti-inflammatory, and wound-healing effects by stimulating cell proliferation and collagen synthesis. It also forms a protective layer on the skin and can act as a mild chemical exfoliant.
Research
Clinical Evidence
Medium confidence5%
Key findings
- 01 5% extract combined with Aloe vera improved fibroblast proliferation, collagen synthesis, and re-vascularization in rat skin injuries.
- 02 5% nano-emulsion of the extract showed high rates of re-epithelialization and inflammation reduction in oral wounds in a rat model.
- 03 1.0 mg/mL (dry weight) stimulated wound healing in an ex-vivo porcine wound-healing model with both ethanol and water extracts.
Transparency
Dusting Analysis
No specific data regarding dusting practices for Plantago Major Leaf Extract was found in the provided research.
The Formula
Formulation
Stability
Nano-emulsions at lower concentrations (e.g., 5%) may offer better drug release and penetration compared to higher concentrations (10-20%).
Synergies
- Aloe vera
Safety
Safety Profile
Topical Plantago major cream is possibly safe for up to two weeks, but it can cause allergic skin reactions in some individuals.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Plantago Major Leaf Extract is a valuable ingredient for soothing and repairing skin, offering antioxidant and anti-inflammatory benefits, particularly beneficial for oily and sensitive skin types.
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References
Sources