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PLANTAGO ASIATICA LEAF/STEM EXTRACT.

Valuable / HUMECTANT, SKIN CONDITIONING

Plantago Asiatica Leaf/Stem Extract is a multifaceted botanical ingredient recognized for its soothing, antioxidant, and brightening properties. Rich in flavonoids, it supports skin regeneration, firmness, and barrier function while helping to reduce irritation. Its comprehensive benefits contribute to enhanced skin health and radiance.

Summary

skin conditioning humectant antioxidant anti-inflammatory soothing whitening collagen boosting skin barrier support

Science

Mechanism of Action

This botanical extract functions as a comprehensive skin conditioner, offering soothing and moisturizing benefits. Its high antioxidant content, featuring flavonoids like aucubin, chlorogenic acid, and quercetin, actively defends the skin against free radical damage. Anti-inflammatory actions, demonstrated by inhibiting nitric oxide generation, help calm redness and irritation. Specific active compounds stimulate collagen synthesis, promoting skin regeneration, firmness, and elasticity, while also contributing to skin barrier restoration. Furthermore, it exhibits a skin-brightening effect by inhibiting tyrosinase, the enzyme responsible for melanin production, and natural mucilage provides additional softening and conditioning.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Inhibited nitric oxide (NO) generation by 31% in LPS-induced RAW 264.7 cells, demonstrating significant anti-inflammatory effects. This concentration also suppressed melanin formation by 29% in B16 F10 melanin cells, indicating a notable skin-whitening potential. Cell viability remained over 75%, confirming safety at this level.
  2. 02 Exhibited substantial antioxidant activity with a reducing power of 3.5. Its free radical scavenging activity (EDA) was concentration-dependent, ranging from 59.32% to 70.30%, highlighting potent antioxidant properties.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Formulators should be aware that this ingredient may present aesthetic or stability challenges that could impact its practical application in formulations.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has not specifically assessed Plantago Asiatica Leaf/Stem Extract. However, it is generally considered non-irritating, with SkinSAFE classifying it as 'Teen SAFE' and free from common irritants such as parabens and coconut. EWG rates its overall concern level as 'LOW' across categories including cancer and immunotoxicity. While generally safe, formulators should note potential aesthetic or stability issues and exercise caution when combining it with other potentially problematic ingredients.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Plantago Asiatica Leaf/Stem Extract is a valuable botanical ingredient, offering proven anti-inflammatory, antioxidant, and brightening benefits alongside skin-soothing and collagen-boosting properties.

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