Science
Mechanism of Action
This extract exerts its benefits primarily through its rich phytochemical composition, including phenolics, flavonoids, and terpenoids. It functions as an antioxidant by efficiently scavenging free radicals such as DPPH and hydrogen peroxide, thereby mitigating oxidative stress. Its anti-inflammatory properties are supported by its traditional medicinal applications and the established activities of its constituent compounds. Furthermore, it demonstrates antimicrobial efficacy against various bacteria, including Porphyromonas gingivalis, Streptococcus mutans, and Streptococcus salivarius. Additionally, it may contribute to skin conditioning and emollient effects, promoting skin comfort and smoothness.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Demonstrated 50% DPPH radical scavenging activity at a concentration of 0.01434%, indicating significant antioxidant potential.
- 02 Achieved 50% hydrogen peroxide scavenging activity at a concentration of 0.004629%, confirming its antioxidant capacity.
- 03 Exhibited a Minimum Inhibitory Concentration (MIC) of 0.1% and a Minimum Bactericidal Concentration (MBC) of 0.3% against Porphyromonas gingivalis, showcasing its antimicrobial action.
Transparency
Dusting Analysis
No specific data available to suggest this ingredient is commonly 'dusted' or used at ineffective concentrations in formulations.
The Formula
Formulation
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) has not specifically evaluated PITTOSPORUM TOBIRA BRANCH/LEAF EXTRACT for cosmetic use safety. General toxicological assessments for the Pittosporum genus are recommended. Acute toxicity studies in mice indicated a lethal dose (LD50) exceeding 1000 mg/kg body weight, suggesting a low acute toxicity profile. However, specific human safety and sensitization data are currently unavailable.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Pittosporum Tobira Branch/Leaf Extract is a valuable botanical ingredient offering demonstrated antioxidant, antimicrobial, and potential anti-inflammatory benefits, making it suitable for a range of precision skincare applications.
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