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Moumoujus

PISUM SATIVUM CALLUS EXTRACT.

Valuable / ANTIMICROBIAL, ANTIOXIDANT, HAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING

Pisum Sativum Callus Extract is a sophisticated, plant-derived ingredient sourced from pea plant stem cells. It is engineered to deliver comprehensive benefits for skin health, acting as a potent anti-aging agent through its support of structural proteins and providing extensive skin conditioning properties.

Summary

Anti-aging Skin Conditioning Antioxidant Humectant Soothing Anti-inflammatory Antimicrobial

Science

Mechanism of Action

This extract operates as a powerful anti-aging and skin conditioning agent by actively inhibiting protease enzymes responsible for the degradation of vital skin components like collagen and elastin, thereby preserving the skin's natural elasticity and firmness. It significantly promotes the biosynthesis of various collagen types (Type 1, Type 3, Type V), elastin, and glycosaminoglycans (GAGs), all crucial for maintaining dermal structure. Furthermore, Pisum Sativum Callus Extract exhibits antioxidant capabilities, attributed to compounds such as ellagic acid, beta-sitosterol, gallic acid, and quercetin, which help reduce factors leading to skin redness and sensitivity. Its humectant properties contribute to enhanced moisture retention, fortifying the skin's natural barrier, while also offering soothing and anti-inflammatory effects and potential antimicrobial activity against acne-causing bacteria due to phytoalexins.

Research

Clinical Evidence

Medium confidence
Effective range 3–10%
Optimal

10%

Key findings

  1. 01 Experiments utilizing a related Pisum Sativum Extract (Pea-Ex™) at concentrations up to 10% demonstrated a 23% increase in cell vitality, a 12% boost in enzymatic activity, and a remarkable 60% rise in protein levels.
  2. 02 This extract was shown to significantly stimulate the synthesis of key structural components including Type 1 Collagen, Type 3 Collagen, Type V Collagen, Elastin, and Glycosaminoglycans (GAGs).
  3. 03 It exhibited anti-elastase activity, providing protection for 50% of papillary elastic fibers and 35% of reticular elastic fibers from enzymatic destruction.
  4. 04 Pisum Sativum extract also led to a time- and dose-dependent improvement in skin tone and offered suggested protection against UV-induced damage.

Transparency

Dusting Analysis

Not commonly dusted

There is no available data regarding the potential for dusting or associated thresholds for Pisum Sativum Callus Extract.

The Formula

Formulation

Solubility
Water
Optimal pH 3 – 7
0 7 14

Stability

The ingredient maintains optimal stability within a pH range of 3 to 7. It should be dispersed in water and incorporated during the final phase of formulation, ensuring temperatures do not exceed 40-45°C to preserve its integrity.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has not specifically evaluated Pisum Sativum Callus Extract, and it is listed as 'Not rated' by Paula's Choice. While the FDA has approved plant protein products as food additives, this does not directly apply to its cosmetic use. No specific GHS classification or dermal toxicity data were found for this extract. However, related Pisum Sativum Extract is generally considered non-irritating, suggesting a low sensitization risk for the callus extract as well.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Pisum Sativum Callus Extract is a valuable, multi-functional ingredient that significantly supports skin's structural integrity, offers robust antioxidant protection, and enhances overall skin vitality and tone across various skin types.

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