Science
Mechanism of Action
This extract functions through a multi-faceted approach, attributed to its rich composition of phenolic compounds like flavonoids, tannins, gallic acid, and rutin, along with anthocyanins. It neutralizes reactive oxygen species and free radicals, acting as a powerful antioxidant by both hydrogen transfer and metal chelation. Its anti-inflammatory action involves inhibiting protein denaturation, suppressing pro-inflammatory prostaglandin synthesis, and acting as a dual COX-2 and LOX inhibitor within the arachidonic acid cascade. Furthermore, it modulates elastase and tyrosinase activities to improve skin elasticity and reduce hyperpigmentation, and provides astringent effects to refine pores and minimize shine.
Research
Clinical Evidence
Medium confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The phenolic compounds abundant within the extract are susceptible to degradation from heat, light, oxygen, and pH fluctuations, potentially necessitating encapsulation for enhanced stability in cosmetic formulations. While these compounds can interact with lipid bilayers, the extract itself is primarily water-soluble.
Safety
Safety Profile
No formal safety assessments from CIR, SCCS, or FDA are currently available for Pistacia Lentiscus Leaf Extract. In vitro toxicity tests indicated no toxicity at an extract concentration of 100 μg/mL. Expert classifications suggest it is generally non-irritating. However, it is important to note that studies on *Pistacia lentiscus fatty oil*, a related but distinct ingredient, have suggested a minimal irritation risk in single exposure but potential for sensitization or irritant contact dermatitis with prolonged use.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Pistacia Lentiscus Leaf Extract is a valuable botanical ingredient offering a broad spectrum of benefits, including potent antioxidant, anti-inflammatory, and anti-aging effects, making it suitable for diverse skin concerns across all skin types with a generally low irritancy profile.
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References
Sources