Science
Mechanism of Action
Derived from *Pistacia lentiscus* leaves, this ingredient is linked to antioxidant, anti-inflammatory, and antimicrobial properties. It is understood to possess astringent effects, contributing to pore tightening and skin shine reduction. Furthermore, it may exhibit anti-aging capabilities by inhibiting elastase, an enzyme crucial for elastin degradation, thus potentially improving skin elasticity. The ingredient's source plant is also implicated in inhibiting tyrosinase, an enzyme involved in melanin production, suggesting potential for pigmentation correction. The essential oil from the lentisque leaf further promotes tissue regeneration, aiding in addressing premature skin aging, stretch marks, and soothing irritated skin.
Research
Clinical Evidence
Low confidenceN/A
Key findings
- 01 Showed transdermal diffusion when formulated into a 5% EAE-hydro-cream.
- 02 Demonstrated 12% elastase inhibition; isolated fractions FC and FM2 showed 42% and 29% inhibition respectively. IC50 values for elastase inhibition were 19 µg/mL for EAE, 86 µg/mL for FC, and 45 µg/mL for FM2.
- 03 Promoted wound healing by accelerating wound contraction and reducing the epithelialization period.
- 04 Used for pore-tightening due to astringent properties and exhibited antimicrobial effects on skin.
Transparency
Dusting Analysis
No specific data regarding 'dusting' properties for PISTACIA LENTISCUS LEAF CERA is available.
The Formula
Formulation
Stability
The phenolic compounds abundant in *Pistacia lentiscus* leaves are susceptible to degradation from heat, light, and oxygen exposure, suggesting potential need for encapsulation to ensure stability within formulations.
Safety
Safety Profile
PISTACIA LENTISCUS LEAF CERA is identified in CosIng for Skin Protecting and Viscosity Controlling functions. While GHS Classification for 'Pistacia lentiscus leaf extract' showed no specific hazards, 'Pistacia lentiscus leaf oil' and volatile components in 'Pistacia lentiscus gum' have been associated with potential skin irritation (Xi R38). No dedicated CIR, SCCS opinions, or FDA status for the CERA form are currently available beyond its CosIng listing.
Your Skin
Skin Compatibility
Our Assessment
Verdict
While *Pistacia lentiscus* extracts and gum exhibit promising bioactive properties, direct clinical efficacy and optimal usage concentrations for PISTACIA LENTISCUS LEAF CERA specifically require further research to validate its role beyond viscosity control and skin protection.
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