Science
Mechanism of Action
This ingredient operates by inhibiting 5α reductase type I, a key enzyme involved in sebum synthesis, which directly contributes to reduced oiliness, minimized pore appearance, and a decrease in skin shine. It possesses inherent antimicrobial capabilities, assisting in the management of surface bacteria, and exhibits anti-inflammatory qualities that calm and soothe irritated skin. Rich in antioxidants, it actively defends against free radical damage and oxidative stress, supporting overall skin health and contributing to anti-aging benefits. Furthermore, it aids in the skin's natural healing processes and can enhance collagen production for improved skin integrity.
Research
Clinical Evidence
Medium confidence2%
Key findings
- 01 As an active ingredient within the PoreAway complex, it demonstrated significant pore refinement, reducing pore size by 8% after 14 days and further by 15% after 28 days of use.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Considerations for formulation stability should include the potential for lower solubility of mastic at acidic pH levels.
Conflicts
- Fragrance-sensitive individuals (due to the presence of volatile, fragrant compounds and documented co-reactivity with various fragrance-related materials).
Safety
Safety Profile
While dermal toxicity studies indicate low acute toxicity (LD50 > 5000 mg/kg in rabbits) and it has shown no genotoxic or mutagenic activity, the volatile and fragrant compounds within the extract carry a potential for skin irritation. Patch testing on allergic individuals revealed that 72% of those allergic to a branded mastic resin product also reacted to gum mastic, suggesting a relevant co-reactivity with fragrance materials and a moderate sensitization risk for predisposed individuals. The CIR status is 'not reviewed' for this specific ingredient, although the broader 'Plant Polysaccharide Gums' category was deemed to have 'insufficient data' in a 2014 assessment.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Pistacia Lentiscus Gum Water is a valuable ingredient for balancing oily skin, refining pores, and providing antioxidant and anti-inflammatory benefits, though individuals sensitive to fragrances should exercise caution.
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