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Moumoujus

PISTACIA LENTISCUS GUM.

Valuable CAS 61789-92-2 / FILM FORMING, FRAGRANCE

Pistacia Lentiscus Gum, derived from the mastic tree, is a versatile ingredient adept at refining skin texture and managing excess oil. It actively diminishes pore appearance and shine, while providing antioxidant protection and anti-inflammatory support.

Summary

Antioxidant Astringent Sebum Regulation Pore Refinement Anti-inflammatory Antimicrobial Collagen Support GAG Synthesis Enhancement Film-forming

Science

Mechanism of Action

This botanical gum operates by precisely targeting sebum overproduction through the inhibition of 5α reductase type I, an enzyme critical in converting testosterone to dihydrotestosterone (DHT). This action effectively reduces oil secretion and visibly tightens dilated pores. Beyond sebum regulation, it imparts antioxidant and anti-inflammatory benefits, exhibits antimicrobial properties, and contributes to skin structure by supporting collagen and glycosaminoglycan synthesis. Its film-forming capacity further enhances skin's refined appearance.

Research

Clinical Evidence

Medium confidence
Effective range 2–4%
Optimal

2%

Key findings

  1. 01 At a 2% concentration, when formulated within a skincare complex, Pistacia Lentiscus Gum demonstrated significant pore refinement, reducing pore size by 8% after 14 days and 15% after 28 days in manufacturer-conducted in-vivo testing.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH 4 – 8
0 7 14

Stability

Maintains stability within a pH range of 4.0 to 8.0. As a natural resin, it is inherently hydrophobic and oil-soluble. For effective incorporation into aqueous systems or water dispersion, specialized formulation techniques are required, such as micronization with hydrophilic polymers or the use of emulsifiers like phospholipid lecithin or specific fatty acid esters.

Conflicts

  • Its volatile, fragrant compounds may elicit skin irritation, particularly in sensitive individuals or those with known fragrance allergies. Patch testing has indicated a high potential for contact allergy, often with co-reactivity to various fragrance-related materials.

Safety

Safety Profile

CIR Status
Not reviewed
Pregnancy
Caution
Sensitization risk Moderate

The Cosmetic Ingredient Review (CIR) has not published a definitive safety assessment for Pistacia Lentiscus Gum. While generally rated low by EWG for broader toxicological concerns, specific data from Paula's Choice and patch testing highlight a potential for skin irritation due to its volatile, fragrant constituents, with a reported 72% contact allergy rate in a subset of fragrance-sensitive patients. The European Medicines Agency (EMA) explicitly advises against its use during pregnancy and lactation due to insufficient genotoxicity and reproductive toxicity data.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Medium
Comedogenicity Low

Our Assessment

Verdict

Valuable

Pistacia Lentiscus Gum is a valuable ingredient for targeting oily and normal skin concerns, effectively reducing pore size and sebum production while offering antioxidant and anti-inflammatory benefits, though caution is advised for sensitive skin and during pregnancy.

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