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Moumoujus

PISCUM IECUR OIL.

Valuable CAS 8009-00-5 / SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

PISCUM IECUR OIL, also known as Cod Liver Oil, is a lipid-rich active ingredient renowned for its comprehensive skin-caring properties. It functions as an effective emollient and occlusive agent, providing barrier support, intense moisturization, and promoting skin health through its rich profile of omega-3 fatty acids, Vitamin A, and Vitamin D.

Summary

Emollient Skin Conditioning

Science

Mechanism of Action

This oil enhances skin hydration by increasing its water content and forming a protective surface barrier, thereby minimizing transepidermal water loss. Its high concentration of omega-3 fatty acids, specifically EPA and DHA, helps mitigate cutaneous inflammation by moderating inflammatory pathways and eicosanoid production, supporting the skin's immune response and wound healing processes. Vitamin A plays a critical role in cellular regeneration, improving skin repair and regulating cell turnover, which contributes to anti-aging benefits. Vitamin D supports healthy skin cell proliferation. Furthermore, PISCUM IECUR OIL aids in collagen synthesis for improved skin plumpness and boosts filaggrin production, a key protein for barrier integrity, particularly beneficial for compromised skin conditions such as psoriasis and atopic dermatitis.

Research

Clinical Evidence

Medium confidence
Effective range 5–30%
Optimal

13.56%

Key findings

  1. 01 Topical application of Cod Liver Oil ointment at 25% and 30% concentrations demonstrated significant acceleration of epithelial and vascular wound healing components in hairless mice.
  2. 02 A 20% (v/v) fatty acid extract derived from Cod Liver Oil exhibited notable in vitro antibacterial activity against several Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pyogenes.
  3. 03 The FDA permits Cod Liver Oil to be utilized in OTC skin protectant products within a concentration range of 5% to 13.56%.

Transparency

Dusting Analysis

Not commonly dusted

There is no available data to suggest that PISCUM IECUR OIL is commonly included in formulations primarily for cosmetic dusting or marketing claims over its functional efficacy.

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

PISCUM IECUR OIL, rich in omega-3 polyunsaturated fatty acids, is inherently prone to oxidation, necessitating careful monitoring of its peroxide value to ensure stability. Formulations containing fatty acid extracts of this oil typically maintain an acidic pH between 4.2 and 5.6, which is generally acceptable for topical dermal applications.

Conflicts

  • Its potent and distinctive fish odor poses a significant challenge for cosmetic acceptability.
  • The ingredient has shown incompatibility with certain waxes, such as carnauba and ozokerite, potentially leading to undesirable rough or gritty textures.
  • When mixed with powdered collagen, oil separation can occur under cooling and pressure conditions.

Safety

Safety Profile

CIR Status
Safe as used
Max tested
13.56%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has deferred its safety assessment of Cod Liver Oil, acknowledging prior evaluation by the FDA. The FDA sanctions its use in OTC skin protectant formulations at concentrations ranging from 5% to 13.56%. In Europe, its inclusion in cosmetic products is permissible, provided it adheres to relevant animal by-products regulations.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

PISCUM IECUR OIL is a valuable multi-functional ingredient offering significant skin barrier support, anti-inflammatory, and wound-healing benefits, with FDA recognition for use in specific topical skin protectant applications.

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