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Moumoujus

PIPER NIGRUM SEED EXTRACT.

Valuable CAS 84929-41-9 / REFRESHING, TONIC

Derived from black pepper seeds, Piper Nigrum Seed Extract is a dynamic botanical ingredient renowned for its antioxidant and anti-inflammatory properties. It actively enhances skin vitality by stimulating microcirculation, refining texture, and mitigating concerns such as hyperpigmentation and enlarged pores, contributing to a visibly revitalized complexion.

Summary

Antioxidant Anti-inflammatory Antimicrobial Microcirculation Stimulant Skin Revitalization Ingredient Absorption Enhancer Collagen Synthesis Support Wound Healing Aid Skin Texture Enhancer Tyrosinase Inhibitor (Melanin Reduction) Erythema Reduction Pore Minimizer Exfoliant Elastase & Hyaluronidase Inhibitor Anti-aging Warming Sensation Perfuming

Science

Mechanism of Action

This extract acts as a potent antioxidant, effectively neutralizing free radicals to protect skin from oxidative damage. Its key active compound, piperine, stimulates microcirculation, which can induce a subtle warming sensation and promote a healthier, revitalized skin appearance. Beyond antioxidant defense, it exhibits anti-inflammatory and antimicrobial actions. It supports dermal regeneration by promoting fibroblast and keratinocyte proliferation, bolstering collagen deposition, and aiding re-epithelialisation for enhanced wound healing. Furthermore, it inhibits tyrosinase activity to reduce melanin content and erythema, visibly decreases the number of pores, and may offer exfoliating benefits. Its capacity to inhibit elastase and hyaluronidase activity contributes to improved skin flexibility and comprehensive anti-aging benefits, while also enhancing the penetration of other active ingredients.

Research

Clinical Evidence

Medium confidence
Effective range 4–5%
Optimal

N/A

Key findings

  1. 01 A Piper nigrum extract loaded emulgel demonstrated significant efficacy on human skin, exhibiting 84% antioxidant activity and 82% tyrosinase inhibition. Topical application led to a measurable decrease in skin melanin content, erythema levels, and the visible number of pores.
  2. 02 Piperine and its derivatives, formulated in a 5% oil-in-water emulsion, exhibited SPF values ranging from 3.15 to 2.73, indicating mild photoprotection, and were confirmed to be non-toxic to skin cells.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

A 4% Piper nigrum extract emulgel maintained physical and chemical stability over 90 days of storage. While pure piperine has limited water solubility (40 mg/L), cosmetic extracts are typically formulated to ensure water compatibility.

Synergies

  • Enhances the absorption of other beneficial skincare ingredients.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Generally recognized as safe for cosmetic use, though a patch test is recommended for individuals with sensitive skin due to a potential mild warming sensation or irritation. The FDA lists black pepper (Piper nigrum L.) as Generally Recognized As Safe (GRAS) for food flavoring. A 90-day subchronic toxicology study in rats established a no-observed-adverse-effect level (NOAEL) of 700 mg/kg/day for a black pepper extract, confirming its non-mutagenic nature in an Ames test up to 5000 µg/plate.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Piper Nigrum Seed Extract is a valuable ingredient, delivering comprehensive benefits including powerful antioxidant protection, skin revitalization, texture refinement, and significant action against hyperpigmentation and enlarged pores, with demonstrated efficacy in clinical studies at low concentrations.

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