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Moumoujus

PINUS THUNBERGII BRANCH/LEAF EXTRACT.

Valuable / SKIN PROTECTING

Pinus Thunbergii Branch/Leaf Extract, derived from the Japanese Black Pine, is a multi-functional botanical renowned for its potent antioxidant and anti-inflammatory capabilities. It actively safeguards the skin from environmental damage, enhances hydration, and supports overall skin vitality.

Summary

Antioxidant Anti-inflammatory Skin conditioning Collagen boosting Moisture retention Antibacterial Skin barrier support Cell repair stimulation

Science

Mechanism of Action

This extract operates by neutralizing harmful free radicals, effectively mitigating oxidative stress within the skin. It demonstrates significant anti-inflammatory effects through the inhibition of key pro-inflammatory pathways, specifically by reducing cytokines such as TNF-α and IL-1β, and suppressing enzymes like COX-2 and PGE2. The extract further supports skin structural integrity by promoting collagen production and improving elasticity via the binding of critical amino acids for collagen and elastin synthesis. It also strengthens the skin's natural barrier, leading to enhanced moisture retention for a softer, more hydrated complexion. Furthermore, it exhibits antibacterial properties that may contribute to acne management, offers supportive UV protection, helps balance skin pH, and stimulates cellular repair.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In an in vitro model using LPS-induced RAW 264.7 macrophages, a 100 µg/mL concentration of Pinus thunbergii leaf ethanol extracts inhibited nitric oxide (NO) production by 53.5% and iNOS expression by 71.5%.
  2. 02 At 100 µg/mL (in vitro), Pinus thunbergii leaf ethanol extracts reduced reactive oxygen species (ROS) generation by 58.2%, suppressed SOD activity by 29.3%, and significantly inhibited pro-inflammatory markers, decreasing COX-2 expression by 83.3% and PGE2 expression by 98.6%.
  3. 03 Topical application of Pinus thunbergii leaf ethanol extracts inhibited arachidonic acid (AA)-induced ear edema in mice by 64.5% at a dose of 1.0 mg/ear (in vivo).

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Pinus Thunbergii Branch/Leaf Extract is generally considered safe for topical application across most skin types and is suitable for daily use, with no widely reported harmful side effects. However, individuals with known allergies to pine or other plant-derived ingredients should perform a patch test prior to widespread use. There are no specific safety assessments from CIR, SCCS, or FDA currently available for this ingredient.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Pinus Thunbergii Branch/Leaf Extract is a valuable botanical offering robust antioxidant and anti-inflammatory benefits, alongside support for collagen, hydration, and overall skin health, making it a promising ingredient for diverse skincare formulations.

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