Science
Mechanism of Action
This extract functions as a powerful antioxidant by effectively neutralizing oxygen free radicals and scavenging DPPH radicals. Its anti-aging efficacy is attributed to stimulating keratinocyte proliferation, promoting the biosynthesis of Type 1 procollagen through the reduction of MMP-I (matrix metalloproteinase-1) activity, and inhibiting elastase and collagenase enzymes, thereby preserving skin's structural integrity. Furthermore, it contributes to overall skin conditioning and moisturization.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Cosmetic compositions incorporating Pinus Koraiensis seed extract within a concentration range of 0.0001% to 25% (wt%) demonstrated significant effects, including accelerated keratinocyte growth, elimination of oxygen free radicals, increased biosynthesis of Type 1 procollagen by reducing MMP-I activity, anti-aging properties, and enhanced skin moisturization.
- 02 An ethylacetate extract of Pinus Koraiensis seed exhibited substantial antioxidant activity, achieving 62.8% DPPH radical scavenging activity at a concentration of 7.0 mg/mL.
- 03 Pinus Koraiensis seed extract, when prepared using ultrasound-assisted extraction (UAE), demonstrated 50% inhibition in antioxidant activity at a concentration of 0.04 mg/mL.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Components of Pinus Koraiensis seed extract demonstrate varying solubilities, allowing for extraction with both polar (water, methanol) and non-polar (ethylacetate, hexane) solvents. While specific optimal pH and stability data for the complete cosmetic ingredient are not explicitly available, related proanthocyanidins from Pinus koraiensis seed scales show favorable antioxidant stability at pH values below 7 and temperatures under 65 °C.
Safety
Safety Profile
A comprehensive safety assessment by the Cosmetic Ingredient Review (CIR) for PINUS KORAIENSIS SEED EXTRACT has not been conducted. Similarly, there is no specific SCCS opinion or FDA status for its topical cosmetic application, indicating that detailed safety parameters, including maximum safe concentration or sensitization potential, remain undefined.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Pinus Koraiensis Seed Extract presents itself as a valuable ingredient, offering significant antioxidant, anti-aging, and moisturizing benefits supported by initial in-vitro and patent data; however, further independent human clinical and safety evaluations would enhance its profile.
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References
Sources