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Moumoujus

PICHIA PASTORIS/SOYBEAN SEED FERMENT LYSATE EXTRACT FILTRATE.

Valuable CAS - / SKIN CONDITIONING

This advanced fermented ingredient, derived from Pichia pastoris yeast and soybean seeds, provides a potent blend of proteins, amino acids, and vital bioactive metabolites. It is precisely engineered to foster skin regeneration, reinforce barrier integrity, and deliver comprehensive soothing and protective benefits.

Summary

Skin Conditioning Antioxidant Humectant Soothing Anti-inflammatory Regenerating Oil Control Skin Protecting Anti-Aging Brightening Allergy Resistance Sunburn Prevention Support Skin Micro-ecology Regulation Skin Barrier Repair Firming

Science

Mechanism of Action

This ingredient actively stimulates cellular turnover and fortifies skin regeneration pathways, leading to measurable improvements in skin texture and overall appearance. Its rich molecular profile, including amino acids and peptides, reinforces the skin's natural barrier, thereby enhancing hydration and moisture retention. Furthermore, it offers robust antioxidant protection against free radical damage and oxidative stress, attributable to phenolic acids and flavonoids from the soybean component. The extract effectively calms irritation and reduces inflammation, contributes to anti-aging by firming the skin and restoring luster through dermal-epidermal junction support, and can aid in oil control by reducing cell lipid secretion. It also shows potential for anti-pigmentation by hindering melanosome transfer, although caution is advised for melasma due to the phytoestrogen content from soy.

Research

Clinical Evidence

Medium confidence
Effective range 1–10%
Optimal

5%

Key findings

  1. 01 A patent application highlights that compositions containing 1-10 wt% of Pichia pastoris fermentation lysate filtrate, with a preferred concentration of 5 wt%, demonstrably confer anti-allergic, anti-inflammatory, sunburn preventive, skin micro-ecology regulating, oil controlling, and skin barrier repairing effects. The filtrate is characterized by its content of total protein, recombinant collagen, polysaccharides, amino acids, and various vitamins.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

No specific optimal pH range for the stability of the final cosmetic extract filtrate has been documented. However, the Pichia pastoris fermentation process itself is typically maintained at a controlled pH of 5.0 ± 0.1.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) Expert Panel has not specifically evaluated 'PICHIA PASTORIS/SOYBEAN SEED FERMENT LYSATE EXTRACT FILTRATE'. Related yeast-derived ingredients, such as 'Pichia Minuta Extract', have shown no mutagenicity in in vitro genotoxicity studies. However, a GRAS notification for 'soybean leghemoglobin from Pichia pastoris' in food noted concerns regarding potential allergenicity for individuals with soy allergies and a lack of long-term toxicity data. Consumers with known soy allergies should exercise caution.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

This multifaceted fermented extract is a valuable ingredient for formulations targeting skin regeneration, barrier repair, and comprehensive protective and soothing benefits across various skin types.

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