Science
Mechanism of Action
Acting as a powerful humectant and skin protectant, Pichia Ferment Lysate Filtrate effectively draws and retains moisture within the skin, preventing transepidermal water loss and strengthening the skin's inherent barrier function. It stimulates cellular turnover, leading to improved skin texture and overall regeneration, while its antioxidant capacity shields the skin from free radical damage. Additionally, it offers anti-inflammatory and soothing benefits, calms irritation, assists in regulating the skin's micro-ecology, and contributes to oil control, anti-aging effects, and skin firming.
Research
Clinical Evidence
Medium confidence5%
Transparency
Dusting Analysis
The identification of an optimal concentration at 5 wt% indicates that Pichia Ferment Lysate Filtrate is intended for use at an efficacious level to deliver its noted benefits, suggesting it is not commonly included merely for minimal label presence.
The Formula
Formulation
Stability
While the optimal pH for the Pichia pastoris fermentation process to maximize recombinant thaumatin production was pH 6.0, no specific optimal pH range for the stability of Pichia Ferment Lysate Filtrate as a finished cosmetic ingredient has been reported.
Safety
Safety Profile
Pichia Ferment Lysate Filtrate is a yeast-derived ingredient included in the CIR's Safety Assessment of Yeast-Derived Ingredients. The Panel concluded that many yeast-derived ingredients, when sourced from species with both dermal sensitization and food use status, are safe in cosmetic applications. While a specific maximum concentration for this ingredient was not explicitly defined, other yeast ferments within the broader assessment were found safe at high concentrations (e.g., up to 90.7%). EWG has noted 'LOW' concerns for Cancer, Allergies & Immunotoxicity, and Developmental and Reproductive Toxicity.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Pichia Ferment Lysate Filtrate is a valuable, multifunctional ingredient that enhances skin hydration, strengthens the barrier, and provides soothing, antioxidant, and anti-aging benefits, making it suitable for a wide range of precision skincare formulations.
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