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PICHIA FERMENT LYSATE FILTRATE.

Valuable / HUMECTANT, SKIN CONDITIONING, SKIN PROTECTING

Pichia Ferment Lysate Filtrate is a bio-fermented ingredient derived from Pichia yeast, offering comprehensive benefits for skin health. It is engineered to boost skin hydration, fortify the natural barrier, and provide significant soothing and protective properties against environmental stressors. This ingredient actively supports skin regeneration and micro-ecological balance.

Humectant Skin Conditioning Agent Skin Protectant Antioxidant Soothing Agent Anti-inflammatory Anti-aging Skin Firming Skin Regeneration Micro-ecology Regulator Oil Control Agent Skin Barrier Repair

Science

Acting as a powerful humectant and skin protectant, Pichia Ferment Lysate Filtrate effectively draws and retains moisture within the skin, preventing transepidermal water loss and strengthening the skin's inherent barrier function. It stimulates cellular turnover, leading to improved skin texture and overall regeneration, while its antioxidant capacity shields the skin from free radical damage. Additionally, it offers anti-inflammatory and soothing benefits, calms irritation, assists in regulating the skin's micro-ecology, and contributes to oil control, anti-aging effects, and skin firming.


Research

Medium confidence
Effective range 1–10%
Optimal

5%


Transparency

Not commonly dusted

The identification of an optimal concentration at 5 wt% indicates that Pichia Ferment Lysate Filtrate is intended for use at an efficacious level to deliver its noted benefits, suggesting it is not commonly included merely for minimal label presence.


The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

While the optimal pH for the Pichia pastoris fermentation process to maximize recombinant thaumatin production was pH 6.0, no specific optimal pH range for the stability of Pichia Ferment Lysate Filtrate as a finished cosmetic ingredient has been reported.


Safety

CIR Status
Safe as used
Sensitization risk Low

Pichia Ferment Lysate Filtrate is a yeast-derived ingredient included in the CIR's Safety Assessment of Yeast-Derived Ingredients. The Panel concluded that many yeast-derived ingredients, when sourced from species with both dermal sensitization and food use status, are safe in cosmetic applications. While a specific maximum concentration for this ingredient was not explicitly defined, other yeast ferments within the broader assessment were found safe at high concentrations (e.g., up to 90.7%). EWG has noted 'LOW' concerns for Cancer, Allergies & Immunotoxicity, and Developmental and Reproductive Toxicity.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

Pichia Ferment Lysate Filtrate is a valuable, multifunctional ingredient that enhances skin hydration, strengthens the barrier, and provides soothing, antioxidant, and anti-aging benefits, making it suitable for a wide range of precision skincare formulations.


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