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PHYTOSTERYL BUTYRATE.

Valuable CAS - / HAIR CONDITIONING, SKIN CONDITIONING

Phytosteryl Butyrate is a versatile ester combining the skin-conditioning benefits of phytosterols with the unique anti-inflammatory properties of butyrate. This ingredient is engineered to enhance skin moisturization, soothe reactive skin, and reinforce the epidermal barrier for improved resilience.

Emollient Skin conditioning Anti-inflammatory Immune-modulating Epidermal barrier support Hair conditioning

Science

This ingredient acts as an emollient, contributing to superior skin moisturization and smoothness. Its key component, butyrate—a short-chain fatty acid—exhibits potent anti-inflammatory and immune-modulating effects. It achieves this by inhibiting pro-inflammatory cytokines and cells, and through histone deacetylase (HDAC) inhibition, it promotes the proliferation of regulatory T cells (Tregs). Furthermore, Phytosteryl Butyrate strengthens epidermal barrier integrity by stimulating the production of critical structural components, including integrin, filaggrin, KRT1, and KRT10, thereby reducing allergen sensitization.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

When encapsulated in liposomes, Phytosterol Butyrate Ester (PBE) demonstrates better storage stability at lower concentrations (e.g., 2.5% to 7.7% PBE/SPC ratio), with higher concentrations (10% PBE/SPC) potentially leading to liposomal structural instability. The inherent odor and instability of free butyric acid are effectively mitigated by its esterification in this form.


Safety

CIR Status
Safe as used
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has affirmed Phytosteryl Butyrate's safety in current cosmetic applications and concentrations, evaluated within the broader context of phytosterols.


Your Skin

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Valuable

Phytosteryl Butyrate is a valuable ingredient, delivering significant emollient, anti-inflammatory, and barrier-strengthening benefits suitable for various skin types with a low risk of irritation.


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