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Moumoujus

PHYLLOSTACHYS NIGRA EXTRACT.

Valuable CAS - / SKIN CONDITIONING

Phyllostachys Nigra Extract is a versatile botanical ingredient renowned for its comprehensive skin benefits. It actively shields the skin from oxidative stress, soothes irritation, and supports an even, radiant complexion. This extract is well-tolerated across all skin types, making it a valuable addition to precision skincare.

Summary

Antioxidant Skin-conditioning Humectant Anti-inflammatory Astringent Brightening

Science

Mechanism of Action

This extract confers its benefits through multiple mechanisms. It provides potent antioxidant protection against free radicals, safeguarding skin from environmental damage and premature aging. Its anti-inflammatory properties effectively reduce redness and calm irritated skin, promoting healthy cellular regeneration. The extract also enhances skin hydration and elasticity, strengthens the skin's protective barrier, and offers a gentle astringent effect that can refine pore appearance. Furthermore, it contains silica, a key mineral supporting collagen production for improved skin firmness over time. Notably, it exhibits anti-melanogenic activity by inhibiting tyrosinase and downregulating MITF via PKA/CREB pathways, contributing to a brighter and more balanced skin tone.

Research

Clinical Evidence

Medium confidence
Effective range ≥0.01%
Optimal

N/A

Key findings

  1. 01 In vitro studies demonstrate potent anti-melanogenic effects, with an IC50 of 0.024% (240 μg/mL) for tyrosinase inhibition.
  2. 02 Confirmed non-cytotoxic at concentrations exceeding 0.01% (100 μg/mL) in B16F10 melanoma cells and up to 0.01% (100 μg/mL) in HepG2 cells.
  3. 03 In human cell models (HaCaT keratinocytes, HMC-1 mast cells) and a murine model, the extract significantly decreased several pro-inflammatory mediators including TARC, GM-CSF, TNF-α, MCP-1, and IL-6, indicating strong anti-inflammatory potential.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

An antioxidant-rich extract, Phyllostachys Nigra Extract is reported as non-toxic. Acute oral toxicity tests in rats and mice showed a maximum tolerated dose greater than 10 g/kg body weight without mutagenic effects. Subchronic administration for up to 90 days established a No-Observed-Adverse-Effect Level (NOAEL) of up to 830 mg/kg body weight per day. Industry assessments, such as INCI Beauty, indicate 'No penalty' across all safety categories.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

With its multifaceted actions encompassing antioxidant protection, anti-inflammatory effects, skin conditioning, and brightening capabilities, Phyllostachys Nigra Extract is a valuable and highly compatible ingredient for enhancing a wide range of precision skincare formulations.

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