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PHRAGMITES KARKA EXTRACT.

Valuable CAS - / SKIN CONDITIONING

Phragmites Karka Extract is a potent botanical ingredient derived from the common reed, celebrated for its robust calming and protective properties. Rich in phenolic compounds and polysaccharides, it actively mitigates inflammatory responses, soothes irritated skin, and reinforces the skin's natural barrier function. This multifaceted extract offers significant benefits for restoring balance and resilience to sensitive and environmentally stressed complexions.

Summary

Skin-Conditioning Agent Soothing Anti-inflammatory Antioxidant Barrier-repairing Moisturizing Microbiome balancing Redness reduction

Science

Mechanism of Action

Phragmites Karka Extract operates through a dual-action mechanism, leveraging its high content of phenolic compounds and polysaccharides. These bioactive components effectively modulate inflammatory pathways, reducing skin irritation and redness. Simultaneously, the extract provides robust antioxidant protection against free radicals and environmental aggressors. It further supports healthy skin by promoting epidermal regeneration, reinforcing the skin barrier, and helping to rebalance the skin's natural microbiome. This comprehensive action results in enhanced skin tolerance and overall resilience.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Topical application of a polysaccharide-rich extract from Phragmites rhizoma significantly suppressed atopic dermatitis-like lesions in NC/Nga mice. This included a notable reduction in dermatitis scores and scratch numbers, attenuated histological manifestations such as epidermal thickening and increased inflammatory cells, and a decrease in IgE activation alongside altered cytokine levels (reduced IFN-γ, IL-4, increased IL-10).
  2. 02 As a key component of SyriCalm™ CLR (a blend with Poria Cocos Extract), Phragmites Karka Extract demonstrates strong and broad in vivo and in vitro support for treating and caring for skin stressed by external factors. It effectively reduces skin redness, alleviates irritation, normalizes skin balance, and enhances skin tolerance to external stresses.

Transparency

Dusting Analysis

Not commonly dusted

Phragmites Karka Extract contains active phenolic compounds and polysaccharides with demonstrated anti-inflammatory, antioxidant, and barrier-supporting properties. Its documented efficacy in pre-clinical models and as a component of validated blends indicates its role as a functional, beneficial ingredient rather than a mere nominal inclusion.

The Formula

Formulation

Solubility
Water
Optimal pH 3 – 8
0 7 14

Stability

When formulated as part of SyriCalm™ CLR, Phragmites Karka Extract maintains stability across a wide pH range of 3.0 to 8.0 without impacting product color or scent. It is soluble in water and water-alcohol mixtures, provided the ethanol concentration does not exceed 50% v/v.

Synergies

  • Poria Cocos Extract (as part of SyriCalm™ CLR blend)

Safety

Safety Profile

CIR Status
Safe as used
Sensitization risk Low

Phragmites Karka Extract, particularly as part of SyriCalm™ CLR, is indicated as CIR Compliant in both the EU and USA. It is described as non-toxic and a non-sensitizer for topical application. Acute toxicity studies showing cellular toxicity with oral administration are not relevant to its intended cosmetic use.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Phragmites Karka Extract is a valuable botanical for strengthening skin resilience, calming inflammation, and protecting against environmental stress, particularly beneficial for sensitive and compromised skin types.

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