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Moumoujus

PHRAGMITES COMMUNIS RHIZOME EXTRACT.

Valuable CAS 84604-02-4 (generic) / ANTIOXIDANT

Phragmites Communis Rhizome Extract is a versatile botanical ingredient renowned for its comprehensive benefits, including superior environmental protection and advanced skin restoration. It effectively supports the skin's natural resilience, calms irritation, and offers significant photoprotective and anti-aging properties.

Summary

Skin conditioning Antioxidant Soothing Moisturizing Anti-aging Photoprotective Anti-inflammatory Skin barrier support Microbiome balancing Anti-melanogenesis

Science

Mechanism of Action

This extract exerts its effects through multiple scientifically supported pathways. It acts as a potent antioxidant, actively scavenging free radicals to shield the skin from oxidative damage. The ingredient also plays a crucial role in restoring the skin barrier and balancing the skin's microbiome. Its anti-inflammatory actions are evident in the suppression of cyclooxygenase-2 (COX-2) induction, providing a soothing effect. Furthermore, its anti-aging potential is linked to inhibiting matrix metalloprotease (MMP) activity, boosting hyaluronic acid content, and suppressing tyrosinase, which collectively contribute to reducing hyperpigmentation and promoting skin cell regeneration.

Research

Clinical Evidence

Medium confidence
Effective range 25–200%
Optimal

N/A

Key findings

  1. 01 In vitro studies using aqueous extracts (PCWE) demonstrated significant photoprotective effects against UVB-mediated photodamage in human dermal fibroblasts (HDFs), melanocytes (B16F10 cells), and keratinocytes (HaCaT cells) at concentrations of 25-200 μg/mL. Key findings included downregulation of MMP-1 expression and elastase activity in HDFs, upregulation of telomerase reverse transcriptase and hyaluronan synthase-2 in HaCaT cells, and suppression of melanin production and tyrosinase activity in B16F10 cells. No significant cytotoxicity was observed up to 200 μg/mL.
  2. 02 Ethanol extracts (PCE) at 25-50 μg/mL effectively inhibited melanin production and cellular tyrosinase activity in B16F10 melanocytes. They also suppressed MMP-1 mRNA expression and reduced elastase activity in HDFs, while mitigating UVB-induced downregulation of hyaluronic acid synthase-2 gene expression in HaCaT keratinocytes. PCE treatment showed no significant cytotoxicity up to 200 μg/mL over 24 hours.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Derived from natural reed plants, Phragmites Communis Extract is generally considered safe for cosmetic applications. Reported instances of allergic reactions are rare, and no serious adverse effects have been noted. Genotoxicity evaluations, including bacterial reverse mutation, chromosomal aberration, and micronucleus tests, performed with an aqueous extract indicated no genotoxic or mutagenic activity, adhering to OECD guidelines and Good Laboratory Practice standards.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Phragmites Communis Rhizome Extract is a valuable ingredient, offering broad-spectrum benefits including robust photoprotection, anti-aging effects, barrier restoration, and soothing properties, making it highly suitable for diverse skin concerns.

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