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PHOENIX DACTYLIFERA SEED EXTRACT.

Valuable CAS 90027-90-0 / MOISTURISING, SKIN CONDITIONING

Phoenix Dactylifera Seed Extract is a botanical active derived from date seeds, celebrated for its robust antioxidant capabilities, anti-melanogenesis effects, and comprehensive anti-aging benefits. It works to protect skin from oxidative damage while visibly addressing hyperpigmentation, supporting overall skin health, even tone, and improved texture. This versatile ingredient also offers notable anti-inflammatory and moisturizing properties.

Summary

Moisturizing Skin Conditioning Antioxidant Anti-aging Anti-inflammatory Skin Brightening Collagen Boosting

Science

Mechanism of Action

This extract primarily functions as an antioxidant by significantly decreasing intracellular reactive oxygen species (ROS) content. It attenuates melanogenesis through the downregulation of protein kinase A (PKA) signaling pathways, which subsequently reduces the expression of key melanin-producing proteins such as MC1R, MITF, tyrosinase, TRP1, and TRP2, positioning it as a potent skin-brightening agent. The extract contains dormins that may slow skin cell proliferation and influence intrinsic aging factors, contributing to a global anti-aging effect and the reduction of concerns like dark circles and rosacea. Furthermore, it possesses emollient, moisturizing, and anti-inflammatory properties, and shows potential to stimulate collagen production, which can lead to improved skin elasticity and firmness.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Demonstrated significant antioxidant activity by reducing intracellular reactive oxygen species (ROS) content in B16F10 murine melanoma cells at concentrations of 0.245 mg/mL and 0.49 mg/mL.
  2. 02 Inhibited melanogenesis in B16F10 cells by decreasing the expression of melanogenesis-related proteins (MC1R, MITF, tyrosinase, TRP1, TRP2) at a concentration of 0.147 mg/mL.
  3. 03 Exhibited significant antioxidant activity, achieving 50% DPPH free radical complexation (IC50) at a concentration of 0.031 µg/mL for an organic seed extract.
  4. 04 Showed significant anti-inflammatory activity, comparable to diclofenac sodium, with extract volumes ranging from 10-50 µL.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

An aqueous extract of Phoenix dactylifera L. seed has been reported with a pH value of 4.67. The chosen solvent system (e.g., water, ethanol, methanol, or their mixtures) significantly impacts the yield and antioxidant activity of the extract; aqueous extracts, for instance, may exhibit lower DPPH antioxidant activity compared to certain ethanol/methanol preparations.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Phoenix Dactylifera Seed Extract is generally regarded as safe and well-tolerated across most skin types, including sensitive skin, with limited evidence of significant adverse effects in cosmetic formulations. No specific regulatory review or status by CIR, SCCS, or FDA (such as 'safe as used' with a maximum concentration) has been explicitly documented.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Phoenix Dactylifera Seed Extract is a valuable, multi-beneficial ingredient offering proven antioxidant, anti-melanogenesis, and anti-inflammatory effects with broad skin compatibility and a low risk of irritation, making it ideal for advanced skincare formulations.

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