Science
Mechanism of Action
Phaseolus Angularis Seed Extract (PASE) functions through several pathways to enhance skin health. It exhibits powerful antioxidant activity by scavenging free radicals and decreasing reactive oxygen species (ROS) generation, thereby protecting the skin from environmental oxidative stress. PASE contributes to anti-aging effects by inhibiting photoaging, downregulating matrix metalloproteinase (MMP)-1 and MMP-3, and significantly increasing procollagen type I production. Its antioxidant properties also stimulate Nrf2-dependent expression of antioxidant enzymes. Additionally, PASE promotes collagen I production by inhibiting UVB-induced TGF-β activation and Smad7 overexpression, offers anti-inflammatory benefits, aids in skin moisturization and elasticity, helps stabilize the skin's oil balance, and supports the removal of dead cells for improved texture. Some extracts also demonstrate antibacterial properties.
Research
Clinical Evidence
Medium confidence0.1%
Transparency
Dusting Analysis
The Formula
Formulation
Stability
While specific optimal pH for Phaseolus Angularis Seed Extract is not explicitly stated, research on related bean extracts indicates formulations can maintain stability regarding phase separation and color changes, with minimal pH alterations, particularly within a basic pH range.
Safety
Safety Profile
Phaseolus Angularis Seed Extract is generally regarded as having a favorable safety profile for cosmetic application. Clinical studies have reported no adverse effects or side effects at a 0.1% concentration. However, individuals with known sensitivities to legumes or particularly sensitive skin may potentially experience mild irritation, redness, or itching. A patch test is recommended prior to extensive use for sensitive individuals. Formal safety assessments by CIR or SCCS are not yet available, and the ingredient is not present on EWG's Skin Deep Restricted or Unacceptable Lists.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Phaseolus Angularis Seed Extract is a valuable ingredient, demonstrating significant anti-aging, antioxidant, and skin-balancing benefits, supported by clinical evidence for wrinkle reduction and a generally favorable safety profile.
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