Science
Mechanism of Action
This ingredient functions by boosting the skin's inherent moisture retention capabilities, primarily by strengthening the lipid barrier and enhancing its water-binding capacity. Its peptides actively restore the skin's protective barrier by filling microscopic gaps and optimizing lipid organization within the stratum corneum. Furthermore, it stimulates fibroblast activity, leading to increased collagen production, which contributes to enhanced skin firmness and elasticity. Rich in essential amino acids, it provides crucial building blocks for protein synthesis, supporting natural skin repair and regeneration while forming a protective film to preserve moisture.
Research
Clinical Evidence
High confidence5%
Key findings
- 01 Clinical studies demonstrate that hydrolyzed keratin nano peptides, used in concentrations ranging from 0.5% to 5%, can achieve up to a 40% improvement in skin hydration levels by strengthening the lipid barrier and enhancing the skin's water-binding capacity.
- 02 Topical application of hydrolyzed keratin peptides with a molecular weight under 1000 Da has been shown to notably increase both skin hydration and elasticity.
- 03 An efficacy study using 3% hydrolyzed keratin in a hand cream reported moisturizing benefits with no adverse effects, confirming its hydrating properties.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
For optimal stability, store this ingredient at or below 24°C in a cool, dry, well-ventilated environment. Avoid temperatures exceeding 40°C, freezing, and prolonged direct sunlight exposure.
Conflicts
- Concentrated nitric acid
- Concentrated sulfuric acid
- Strong oxidizing agents
- Gross bacterial contamination
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel concluded that hydrolyzed keratin and its derivatives are safe for use in cosmetics at present concentrations. Human studies indicate no irritation at concentrations up to 25%, and in vitro tests showed minimal to no irritation. The risk of sensitization is low, with no sensitization observed in human repeat insult patch tests up to 5% or in guinea pig studies up to 25%. While an isolated allergic reaction was reported with a hair conditioner containing hydrolyzed keratin, the nano peptides generally exhibit an excellent safety profile, making them suitable for sensitive skin types.
Your Skin
Skin Compatibility
Our Assessment
Verdict
PG-HYDROLYZED KERATIN is a valuable ingredient for significantly enhancing skin hydration, strengthening the epidermal barrier, and improving elasticity, boasting a strong safety profile suitable for most skin types.
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