Science
Mechanism of Action
PG-HYDROLYZED COLLAGEN, with propylene glycol serving as an alcoholic component, primarily exerts its effects through its hydrolyzed collagen content. It acts as a powerful humectant and moisturizer, actively attracting and binding water to the skin's surface, thereby enhancing hydration. The ingredient forms a protective, non-occlusive barrier that effectively minimizes transepidermal water loss. Its low molecular weight (3-6 kDa) allows it to efficiently penetrate the skin's upper layers, delivering free amino acids that serve as building blocks for the skin's natural collagen and elastin fibers. Furthermore, its collagen oligopeptides are understood to stimulate fibroblasts, promoting the endogenous production of new collagen, elastin, and hyaluronic acid, which collectively support the skin's connective tissue, restoring suppleness, elasticity, and reducing the appearance of dryness and flaking.
Research
Clinical Evidence
Low confidenceN/A
Key findings
- 01 Oral hydrolyzed collagen supplements (5g daily) improved skin hydration, elasticity, smoothness, firmness, and reduced wrinkle visibility over 28-56 days.
- 02 An oral hydrolyzed collagen peptide supplement (CollaSel Pro®) significantly ameliorated skin roughness from week 1, with continued improvement up to week 12.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Hydrolyzed collagen is highly soluble in both cold and hot water. Its relatively low molecular weight (3-6 kDa) compared to native collagen enhances its solubility and reduces viscosity in aqueous solutions. Optimal stability is maintained within a pH range of 5.0-6.5, with an isoelectric point typically between 3.68 and 5.7.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has deemed hydrolyzed collagen safe for cosmetic use within current practices and concentrations, with typical usage rates ranging from 0.2-2.0%. Clinical evaluations have consistently shown no evidence of skin sensitivity, phototoxicity, or irritation. The FDA also classifies gelatin, a precursor to collagen peptides, as a safe substance, reinforcing its safety for dermal application.
Your Skin
Skin Compatibility
Our Assessment
Verdict
PG-HYDROLYZED COLLAGEN is a valuable ingredient for improving skin hydration, texture, and suppleness due to its humectant, emollient, and film-forming properties, making it beneficial for most skin types.
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