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Moumoujus

PFAFFIA GLOMERATA ROOT JUICE.

Valuable CAS - / SKIN CONDITIONING

Derived from the root of the 'Brazilian ginseng' plant, Pfaffia Glomerata Root Juice is a multifaceted ingredient recognized for its robust antioxidant, anti-inflammatory, and skin-regenerating capabilities. It is utilized in skincare to help calm irritation, promote healing, and fortify the skin against environmental stressors.

Summary

Skin conditioning Antioxidant Anti-inflammatory Skin regenerating Antibacterial

Science

Mechanism of Action

This root juice delivers its benefits through a rich profile of bioactive compounds, including β-ecdysone, phenolic acids (such as gallic acid), saponins, and flavonoids. β-ecdysone specifically contributes to antioxidant defenses, supports wound healing, and promotes cellular regeneration. Saponins and phenolic compounds further contribute to antibacterial action, while the adaptogenic properties of the plant may enhance the skin's resilience.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Oral administration of Pfaffia glomerata root extract at 100-300 mg/kg demonstrated anti-inflammatory and antinociceptive effects in carrageenan-induced rat paw edema models. A 100 mg/kg oral dose inhibited granulomatous tissue formation by 29%, showing a dose-dependent anti-inflammatory response.
  2. 02 β-ecdysone, a key compound naturally present in Pfaffia glomerata, is associated with significant antioxidant activity, wound-healing, and skin-regenerating properties. Its inclusion in cosmetic preparations is noted for these benefits.
  3. 03 A Pfaffia glomerata leaf extract exhibited antibacterial activity against Escherichia coli and Pseudomonas aeruginosa, with a Minimum Inhibitory Concentration (MIC) of 20 mg/mL.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) has classified 'PFAFFIA GLOMERATA ROOT JUICE' with 'No Reported Uses' under the FDA's Voluntary Cosmetics Reporting Program, indicating that further review is not currently deemed necessary. The US FDA approved Pfaffia glomerata as a healthy food item in 1994, which refers to oral consumption, not specific topical cosmetic application.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Pfaffia Glomerata Root Juice is a valuable botanical ingredient, offering multifaceted benefits for skin health through its antioxidant, anti-inflammatory, and regenerative properties, with broad compatibility across all skin types.

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