Science
Mechanism of Action
This extract operates by directly scavenging ABTS radicals, thereby contributing to its antioxidant efficacy. Its anti-inflammatory action is evidenced by the inhibition of nitric oxide production, a key mediator in inflammatory pathways. While screened for anti-wrinkle (elastase inhibition) and skin brightening (tyrosinase inhibition) effects, these activities were less pronounced or required notably higher concentrations in preliminary assessments.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 An in-vitro assay revealed anti-inflammatory activity, demonstrating inhibition of nitric oxide (NO) production at a concentration of 65.7 ± 12.3 μg/mL.
- 02 Antioxidant efficacy was observed in an ABTS radical scavenging assay, with activity demonstrated at 49.4 ± 0.2 μg/mL.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The optimal pH range for the extract's stability is not definitively established in current literature. However, consistent with general cosmetic formulation practices, a pH range of 5 to 6.5 is often targeted for product stability and optimal skin compatibility. Its observed solubility in water and hydro-ethanolic solutions suggests adaptability within various aqueous-based formulations.
Safety
Safety Profile
Comprehensive safety assessments by regulatory bodies such as CIR, SCCS, or FDA for Persicaria Thunbergii Extract are not currently available in the reviewed data. Therefore, its maximum safe concentration and long-term sensitization potential remain to be thoroughly evaluated.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Persicaria Thunbergii Extract presents as a valuable botanical, offering scientifically-backed antioxidant and anti-inflammatory benefits, though further in-vivo studies and comprehensive safety evaluations would strengthen its profile.
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References
Sources