Science
Mechanism of Action
This extract functions primarily through its high concentration of flavonoids, such as quercetin, and other phenolic compounds, which impart significant antioxidant and anti-inflammatory effects. Additionally, it demonstrates antimicrobial action against various microorganisms, including *Staphylococcus aureus*, *Enterococcus faecalis*, *Escherichia coli*, and the fungal species *Pityrosporum ovale*.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 A 15% ethanol extract of Persicaria minor leaves, when incorporated into a shampoo formulation, demonstrated significant antifungal activity against *Pityrosporum ovale*, achieving an inhibitory zone diameter of 2.61 cm.
- 02 A methanolic extract of Persicaria minor displayed strong antioxidant capacity with an IC50 value of 0.39 mg/mL for DPPH radical scavenging, indicating effective activity as values below 10 mg/mL are considered potent.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Bioactive compounds from Persicaria minor are effectively extracted using ethanol or aqueous-ethanol solvents, with 70% methanol specifically noted as a suitable solvent for maximizing the extraction of compounds relevant for biological activity studies.
Safety
Safety Profile
While the Cosmetic Ingredient Review (CIR) has not assessed this ingredient, 'Persicaria Minor Leaf/Stem Extract' is authorized in the European Union for its antioxidant function in cosmetic products. In the U.S., 'Persicaria minor whole' is listed in the FDA's Global Substance Registration System, and a branded ingredient (BioKesum®) has a self-determined GRAS status, though the generic extract is not found in major FDA databases for dietary supplements or GRAS substances.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Persicaria Minor Leaf/Stem Extract is a valuable botanical offering potent antioxidant, anti-inflammatory, and antimicrobial benefits, making it suitable for a range of protective and restorative skincare applications.
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References
Sources