Science
Mechanism of Action
This ingredient acts through a rich array of bioactive compounds, notably flavonoids and polyphenols, which confer powerful antioxidant protection against free radicals and premature aging. Its anti-inflammatory capabilities soothe irritated skin and visibly reduce redness. The presence of linolenic acid is crucial for restoring the skin barrier and fortifying its protective functions. Furthermore, Perilla Ocymoides Leaf Powder stimulates collagen production and helps preserve hyaluronic acid levels by upregulating hyaluronan synthase 2 (HAS2) and 3 (HAS3), thereby boosting skin hydration. It also contributes to forming a protective barrier that prevents moisture loss and defends against external aggressors like allergens and bacteria. Rosmarinic acid, a key active, demonstrates anti-allergic properties and has shown anti-carcinogenic potential, inhibiting inflammatory cell migration and lesion exacerbation.
Research
Clinical Evidence
Medium confidence0.2%
Key findings
- 01 A clinical evaluation on thirty healthy volunteers aged 40-60 demonstrated that a serum containing 0.2% Perilla frutescens leaves extract significantly increased skin hydration and elasticity after 8 weeks, with no reported skin irritation or allergic reactions. The broader recommended dosage range for Perilla Ocymoides Leaf Extract in various product types is 0.01-0.2%.
Transparency
Dusting Analysis
As a powder, there are documented concerns regarding respiratory issues if this ingredient is used in inhalable forms. This necessitates careful consideration for formulations that could lead to airborne particles.
The Formula
Formulation
Stability
A serum containing Perilla frutescens leaves extract was found stable at pH 6.0 under various storage conditions for 3 months. However, the anthocyanins, which contribute to the leaves' color, are highly susceptible to degradation under high pH, light exposure, heat, and ionizing substances, emphasizing the need for thoughtful formulation to preserve the ingredient's integrity.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) has not specifically reviewed 'PERILLA OCYMOIDES LEAF POWDER' for cosmetic safety. It is listed on EWG Skin Deep with 'moderate' concerns for allergies/immunotoxicity and 'use restrictions', noting that its score is higher if used in inhalable forms (e.g., powders) due to respiratory concerns. While 'Perilla Ocymoides (Beefsteak Plant) Leaf Extract' carries high use restrictions according to EWG, the extract form is generally recognized as safe for specific food uses by the US FDA.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Perilla Ocymoides Leaf Powder is a valuable active ingredient for skincare, offering comprehensive benefits including antioxidant protection, soothing anti-inflammatory action, enhanced hydration, and barrier support, though its use in inhalable forms should be carefully considered due to potential respiratory concerns.
Related
Similar Ingredients
Finding similar ingredients…