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Moumoujus

PERILLA OCYMOIDES LEAF EXTRACT.

Valuable CAS 90082-61-4 / TONIC

Perilla Ocymoides Leaf Extract is a multi-functional botanical recognized for its potent antioxidant and anti-inflammatory properties. It actively combats free radical damage, soothes irritation, and supports optimal skin hydration and barrier function. This makes it a versatile ingredient suitable for addressing a broad spectrum of skin concerns, including aging, sensitivity, and dryness.

Summary

Antioxidant Anti-inflammatory Humectant Moisturizing Anti-aging DNA Repair Enhancement Barrier Support

Science

Mechanism of Action

This extract leverages its rich composition of flavonoids and polyphenols to deliver powerful antioxidant effects, neutralizing free radicals and protecting against premature aging and UV-induced damage, while also reducing reactive oxygen species (ROS) and enhancing DNA repair processes. As an anti-inflammatory agent, it calms irritated skin by reducing redness and inhibiting key inflammatory mediators such as periostin, TARC, MMP-9, and IL-31. Furthermore, it supports the skin's moisture barrier, preventing transepidermal water loss and defending against external aggressors. It significantly enhances skin hydration by upregulating hyaluronan synthase 2 (HAS2) and hyaluronan synthase 3 (HAS3), enzymes crucial for hyaluronic acid synthesis.

Research

Clinical Evidence

Medium confidence
Effective range ≥0.001%
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

There is no available data to indicate that Perilla Ocymoides Leaf Extract is commonly dusted or to establish a dusting threshold within cosmetic formulations.

The Formula

Formulation

Solubility
Water
Optimal pH 6 – 6
0 7 14

Stability

Formulations containing Perilla frutescens leaves extract demonstrate excellent stability at an optimal pH of 6.0. Tested under diverse storage conditions (room temperature, 4°C, 45°C, and heat/cold cycles), a serum maintained consistent physical properties, including pH and appearance, with no significant changes in viscosity.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

No explicit CIR or SCCS safety assessment is available for Perilla Ocymoides Leaf Extract. While EWG rates it 'MODERATE' for allergies and immunotoxicity, human clinical studies evaluating topical applications of cosmetic serums containing the extract reported no skin irritation or allergic reactions, exhibiting a low Primary Dermal Irritation Index (PDII < 0.5). Information regarding pregnancy safety is not available.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Perilla Ocymoides Leaf Extract is a valuable, versatile botanical offering proven antioxidant, anti-inflammatory, and hydrating benefits for diverse skin types, with a favorable safety profile in topical applications and good formulation stability.

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