Science
Mechanism of Action
Pentasodium Tetracarboxymethyl Hexanoyl Dipeptide-12 functions as an adiponectin-stimulating peptide, playing a role in the skin's defense against UV-induced damage. Fundamentally, this class of peptides signals the body to activate the skin's inherent repair mechanisms, enhancing its structural integrity and potentially contributing to a visible reduction in wrinkles, alongside improvements in overall complexion and elasticity. Similar peptides have also been observed to induce autophagy, which can decrease melanin content by promoting the degradation of melanosomes within melanocytes and keratinocytes.
Research
Clinical Evidence
Medium confidence0.01%
Key findings
- 01 A clinical study evaluated a final formulation containing 0.01% (100 ppm) Pentasodium Tetracarboxymethyl Hexanoyl Dipeptide-12, demonstrating its efficacy in attenuating UV-induced skin damage.
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
No significant adverse effects were reported in clinical studies utilizing this peptide. Additionally, a closely related peptide demonstrated good tolerability in a cream formulation. Comprehensive safety assessments by regulatory bodies such as CIR, SCCS, or FDA specifically for Pentasodium Tetracarboxymethyl Hexanoyl Dipeptide-12 are not currently available.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This adiponectin-stimulating peptide offers significant potential for attenuating UV-induced skin damage and supporting overall skin health and repair.
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References
Sources