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PENTAPEPTIDE-62.

Insufficient Data / ANTIMICROBIAL, HUMECTANT, SKIN CONDITIONING, SKIN PROTECTING

PENTAPEPTIDE-62 is a synthetic, single-chain human peptide produced via E. coli fermentation, with a gene sequence targeting hepatocyte growth factor. It functions to activate the skin's endogenous repair mechanisms, contributing to structural strengthening and the visible reduction of wrinkles, alongside providing antioxidant benefits.

Antioxidant Skin Conditioning Anti-aging

Science

This peptide operates by signaling the skin to initiate its natural repair pathways, promoting the regeneration of mature skin cells. It aids in fortifying the skin's structural integrity, which visibly diminishes the appearance of wrinkles. Additionally, PENTAPEPTIDE-62 exhibits antioxidant properties, helping to protect skin from oxidative stress.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 3 – 5
0 7 14

Stability

PENTAPEPTIDE-62, like other peptides, requires precise pH control for optimal stability. Buffered solutions within a pH range of 3 to 5 are crucial for minimizing deamidation and oxidation, as well as preserving disulfide bridges. Hydrolysis may occur between pH 5-6, and base-catalyzed epimerization is possible above pH 7. Optimal storage conditions involve low temperatures and protection from light to prevent degradation.


Safety

CIR Status
Not reviewed
Sensitization risk Unknown

No specific safety assessments by regulatory bodies such as CIR, SCCS, or FDA have been identified for PENTAPEPTIDE-62 or its related form, SH-POLYPEPTIDE-62. While peptides generally exhibit a favorable safety profile, ingredient-specific review is currently absent for this compound.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

While PENTAPEPTIDE-62 offers promising theoretical benefits as a signaling peptide and antioxidant, the current absence of specific clinical studies and comprehensive safety evaluations necessitates further research for a conclusive efficacy and safety profile.


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