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PENTAPEPTIDE-55.

Insufficient Data / SKIN CONDITIONING

PENTAPEPTIDE-55, identified also as Pentapeptide-1 or sh-Pentapeptide-1, is a synthetic biomimetic peptide specifically designed to enhance skin health by modulating immune responses. It actively soothes sensitive skin and reduces irritation while contributing to a balanced skin microflora.

skin conditioning immunomodulating soothing anti-irritant anti-inflammatory microflora regulation

Science

Derived from thymopoietin, this pentapeptide (Arg-Lys-Asp-Val-Tyr) precisely interacts with the skin's immune system. Its core function involves decreasing levels of the inflammatory cytokine IL-17 and regulating helper T-cell proportions, thereby alleviating inflammation, calming irritation, and fostering an optimal skin environment.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Optimal stability for peptides is often observed in buffer solutions with a pH between 3 and 5, which helps mitigate deamidation and oxidation.


Safety

CIR Status
Not reviewed
Sensitization risk Low

Generally considered safe for use in skincare, with reports indicating no heavy metal contamination or irritation to skin or eyes.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Insufficient Data

This peptide shows strong potential for soothing sensitive and irritated skin by modulating immune responses and supporting a healthy skin microbiome, though more specific clinical studies would solidify its efficacy data.


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