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Moumoujus

PENTAPEPTIDE-11.

Insufficient Data CAS - / SKIN CONDITIONING

PENTAPEPTIDE-11, primarily utilized as its lipopeptide derivative Myristoyl Pentapeptide-11, is a sophisticated signaling peptide designed to enhance the skin's inherent structural integrity. It actively supports the synthesis of critical structural proteins like collagen, promoting improved elasticity and density, while also contributing to skin repair and barrier reinforcement.

Summary

Skin conditioning Anti-aging Firming Elasticity boosting Barrier repair Collagen synthesis support

Science

Mechanism of Action

Myristoyl Pentapeptide-11, an amphiphilic lipopeptide, operates by engaging with crucial extracellular matrix signaling pathways within the skin. It biochemically interacts with fibroblast receptors, modulating cellular communication to stimulate the endogenous production of key collagen types, specifically I, III, IV, and VII. This multifaceted action promotes cellular proliferation, facilitates matrix remodeling, and accelerates tissue repair processes, cumulatively contributing to enhanced skin elasticity, increased compactness, and a visible reduction in the appearance of fine lines. Additionally, it aids in repairing compromised skin and fortifying the skin's protective barrier function.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Myristoyl Pentapeptide-11 possesses an amphiphilic structure, facilitating its compatibility across both aqueous and lipid formulation phases. The myristoyl fatty acid conjugation significantly improves its lipophilicity, which is theorized to enhance skin penetration and impart superior stability compared to the unconjugated peptide.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

While the Cosmetic Ingredient Review (CIR) Expert Panel has assessed the safety of a group of related pentapeptides (including Myristoyl Pentapeptide-4, Palmitoyl Pentapeptide-4, and Pentapeptide-4), Myristoyl Pentapeptide-11 was not explicitly included in these specific assessments. No dedicated safety opinion from SCCS was found for either PENTAPEPTIDE-11 or Myristoyl Pentapeptide-11. The FDA mandates cosmetic ingredients to be safe for their intended use but does not pre-approve them.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

PENTAPEPTIDE-11, typically incorporated as Myristoyl Pentapeptide-11, demonstrates a promising mechanism for collagen synthesis and skin repair. However, comprehensive clinical data for this specific peptide and its optimal concentrations are not provided, leading to an 'insufficient-data' rating.

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