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PENTAERYTHRITYL TETRAETHYLHEXANOATE.

Valuable CAS 7299-99-2 / SKIN CONDITIONING - EMOLLIENT, VISCOSITY CONTROLLING

Pentaerythrityl Tetraethylhexanoate is a sophisticated synthetic ester, highly valued for its emollient and occlusive properties. It creates a biomimetic barrier on the skin, proficiently locking in moisture and preventing transepidermal water loss. Formulations typically incorporate it within a 1-20% concentration for optimal functional benefits, contributing to a smoother, softer complexion and an enhanced product experience.

Summary

emollient occlusive viscosity controlling skin conditioning

Science

Mechanism of Action

This ingredient functions by establishing a protective, occlusive film on the skin's surface, which significantly reduces transepidermal water loss (TEWL) and thus maintains balanced hydration. As a skin conditioning agent, it further refines the texture of cosmetic formulations, improving spreadability and optimizing the absorption of active ingredients for superior product performance.

Research

Clinical Evidence

High confidence
Effective range 0.06–50%
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

Pentaerythrityl Tetraethylhexanoate is an oil-soluble emollient, and as such, is not associated with 'dusting' issues common to certain powdered or active ingredients.

The Formula

Formulation

Solubility
Oil
Optimal pH 3 – 9
0 7 14

Stability

This ingredient maintains stability across a pH spectrum of 3.0 to 9.0. It demonstrates heat tolerance when integrated into the oil phase; however, it is advisable to avoid sustained temperatures exceeding 80°C. It is known to enhance formula texture, promote even spreadability, and is compatible with a diverse array of cosmetic actives.

Safety

Safety Profile

CIR Status
Safe as used
Max tested
50%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has rigorously assessed Pentaerythrityl Tetraethylhexanoate, deeming it safe for use in cosmetic applications at concentrations up to 50%. Its profile indicates a low likelihood of inducing skin irritation or allergic contact dermatitis. SkinSAFE categorizes this ingredient as free from a wide array of common irritants, including fragrance, parabens, lanolin, gluten, soy, propylene glycol, and dyes, making it suitable for sensitive skin populations across all age groups, including infants and expectant mothers (though specific pregnancy safety data is not explicitly available).

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Pentaerythrityl Tetraethylhexanoate is a highly valuable ingredient for its robust emollient and occlusive capabilities, contributing significantly to skin hydration, texture refinement, and overall formula elegance across a broad spectrum of skin types.

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