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PEG/PPG-7/12 DIMETHYL ETHER.

Valuable / SKIN CONDITIONING

This versatile ingredient, also known as EPDME, acts as a sophisticated skin conditioning and emulsifying agent. It is particularly noted for its capacity to fortify the skin's natural barrier and deliver significant, non-sticky moisture, especially benefiting dry skin types.

Summary

Skin Conditioning Emulsifying Surfactant Moisture-Retaining

Science

Mechanism of Action

PEG/PPG-7/12 Dimethyl Ether functions by improving the skin's barrier integrity through enhancing the structured organization of lipid layers within the stratum corneum. Beyond its barrier-supporting role, it also serves as an effective skin conditioning agent, surfactant, and emulsifying component in cosmetic formulations.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Topical application of Polyoxyethylene/Polyoxypropylene Dimethyl Ether (EPDME) has been shown to improve the skin's barrier function by increasing the ordering of intercellular lipid structures in the stratum corneum. This leads to a high moisture-retaining effect without a sticky residue, effectively preventing and ameliorating dry skin conditions with daily application.

Transparency

Dusting Analysis

Not commonly dusted

Information regarding the dusting potential of PEG/PPG-7/12 DIMETHYL ETHER is not available in the provided research data.

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

The ingredient demonstrates general stability across a range of acidic and alkaline pH conditions. In its liquid or solid form, it is considered a flammable material; therefore, direct contact with strong oxidizing agents should be avoided to prevent combustion.

Synergies

  • Glycerol (observed to have a synergistic effect in improving barrier function and moisture retention)

Conflicts

  • Strong oxidants (risk of burning)
  • Damaged skin (topical application should be avoided)

Safety

Safety Profile

CIR Status
Safe as used
Max tested
7%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has deemed PEG/PPG-7/12 Dimethyl Ether safe for use in cosmetics under current practices and concentrations, provided formulations are non-irritating. It is associated with negligible sensitizing potential and very low acute and chronic toxicities on healthy skin. However, the CIR Panel advises caution when formulating with ingredients whose safety is dependent on limited dermal absorption, as some alkyl PEG/PPG ethers may enhance penetration. Manufacturers are also responsible for ensuring the absence of impurities like ethylene oxide and 1,4-dioxane. Application to damaged skin is not recommended.

Your Skin

Skin Compatibility

No Normal
Yes Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

PEG/PPG-7/12 Dimethyl Ether is a valuable ingredient, particularly for dry skin, due to its proven efficacy in enhancing skin barrier function and providing sustained, non-sticky hydration, provided it is formulated responsibly and applied to healthy skin.

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