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PEG/PPG-50/20 TOCOPHERYL ETHER.

Optional CAS - / ANTICAKING, ANTIOXIDANT, BINDING, EMULSION STABILISING, PLASTICISER, SKIN CONDITIONING, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING, UV ABSORBER

PEG/PPG-50/20 Tocopheryl Ether is a synthetic derivative of Tocopherol (Vitamin E), modified with polyethylene glycol (PEG) and polypropylene glycol (PPG) chains. This amphiphilic molecule functions as a versatile ingredient in cosmetic formulations, primarily acting as an antioxidant, surfactant, and skin conditioning agent.

Summary

Antioxidant Surfactant (Emulsifying) Surfactant (Cleansing) Emulsion Stabilizer Plasticizer Skin Conditioning Agent UV Absorber

Science

Mechanism of Action

This compound exerts its effects through multiple mechanisms. It functions as an antioxidant, helping to neutralize reactive oxygen species and mitigate oxidative stress. As a surfactant, it facilitates the emulsification of immiscible liquids and contributes to cleansing. Additionally, it stabilizes emulsions, acts as a plasticizer to impart flexibility, conditions the skin, and demonstrates UV-absorbing properties.

Research

Clinical Evidence

Insufficient-data confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Safe with restrictions
Sensitization risk Moderate

The Cosmetic Ingredient Review (CIR) Expert Panel concludes that PEG/PPG-50/20 Tocopheryl Ether is safe for cosmetic use when formulated to be nonirritating. However, concerns regarding irritation persist for its propylene glycol and polypropylene glycol components. While generally rare in topical applications, PEG-containing excipients have been associated with anaphylactic reactions, typically observed in parenteral formulations. The Environmental Working Group (EWG) has noted 'some' concerns for cancer and reproductive toxicity, and reports skin irritation, although these specific concerns were linked to its use in household cleaners.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Optional

PEG/PPG-50/20 Tocopheryl Ether offers versatile formulation benefits and antioxidant properties, but its direct skin efficacy lacks specific clinical validation and its potential for irritation necessitates careful formulation.

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