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PEG/PPG-240/60 COPOLYMER.

Valuable CAS 9003-11-6 (generic) / SOLVENT

This versatile nonionic polyoxyethylene-polyoxypropylene copolymer is expertly designed to enhance cosmetic and pharmaceutical formulations. It primarily functions as an emulsifier, solubilizer, and thickening agent, contributing to product stability and texture.

Summary

Viscosity controlling Emulsion stabilizing Surfactant Humectant Solubilizing agent Wetting agent

Science

Mechanism of Action

PEG/PPG-240/60 COPOLYMER is a triblock copolymer, featuring hydrophilic polyoxyethylene segments and hydrophobic polyoxypropylene segments. This amphiphilic structure allows it to effectively bridge oil and water phases, acting as a potent emulsifier and solubilizer. It also serves as a thickening agent, lending a desirable 'self-smoothing' or 'memory gel' texture to products, and functions as a wetting agent to improve spreadability. In broader applications, such poloxamers can enhance ingredient penetration by interacting with biological membranes and reducing viscosity.

Research

Clinical Evidence

Insufficient-data confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 5 – 7.5
0 7 14

Stability

Demonstrates excellent stability across a pH range of 5.0-7.5 and high tolerance to salts. It remains stable at temperatures up to 50°C over prolonged periods, effectively supporting emulsion and powder dispersion stability.

Safety

Safety Profile

CIR Status
Unknown
Sensitization risk Low

While specific conclusive safety assessments from CIR or SCCS for PEG/PPG-240/60 COPOLYMER are not explicitly available, the broader class of Polyethylene-polypropylene glycol is widely considered non-toxic and non-irritant. Animal toxicity studies (dogs and rabbits) at concentrations of 5% w/v and 10% w/v indicated it to be non-irritating and non-sensitizing. It is also listed in the FDA Inactive Ingredients Database for various pharmaceutical applications, including topical formulations.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

PEG/PPG-240/60 Copolymer is a valuable formulation asset, significantly enhancing product stability, texture, and sensory attributes across all skin types with a low risk of irritation or sensitization.

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