Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

PEG/PPG-200/70 COPOLYMER.

Valuable CAS 9003-11-6 (generic) / SOLVENT

PEG/PPG-200/70 Copolymer, a type of Poloxamer, is an amphiphilic block copolymer essential for modern skincare formulations. It expertly bridges oil and water phases, acting as a versatile solvent, solubilizer, and emulsifier. This ingredient facilitates the homogenous distribution of active compounds and enhances overall product stability.

Summary

solvent solubilizer emulsifier dispersant formulation stabilizer

Science

Mechanism of Action

Functioning primarily as a solvent and a sophisticated delivery vehicle, PEG/PPG-200/70 Copolymer leverages its unique amphiphilic structure, comprising both hydrophilic polyethylene oxide and hydrophobic polypropylene oxide blocks. This dual nature allows it to solubilize poorly soluble ingredients, disperse pigments, and stabilize emulsions by integrating immiscible components. By enabling optimal ingredient dispersion and stability, it indirectly supports the efficient delivery and bioavailability of other active compounds on the skin.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

This ingredient functions as a formulation aid, such as a solvent or emulsifier, and is not typically used as a standalone active or in a form prone to 'dusting' in formulations.

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Poloxamers are generally stable under standard conditions, though they exhibit 'reverse solubility,' becoming more soluble at lower temperatures. Increased temperature can lead to reduced solubility of the polypropylene oxide block and micelle formation. This copolymer's structure can be influenced by pH, indicating potential pH sensitivity.

Conflicts

  • Strong oxidizing agents are incompatible with Poloxamers.
  • Formulators must ensure rigorous purification to control impurities such as ethylene oxide, propylene oxide, and 1,4-dioxane to established safe limits.

Safety

Safety Profile

CIR Status
Safe as used
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has assessed Poloxamers, including this type, concluding they are not dermal irritants or sensitizers in animal models, with clinical tests showing uniformly negative results for human skin irritation and sensitization. Little skin penetration is predicted due to molecular weight and solubility. While reproductive and developmental toxicity data were not available, the FDA has approved Poloxamers for use in pharmaceuticals, foods, and cosmetics, emphasizing the critical importance of purification to minimize impurities like ethylene oxide, propylene oxide, and 1,4-dioxane.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

PEG/PPG-200/70 Copolymer is a valuable formulation aid, enabling superior stability and efficient delivery of active ingredients by seamlessly blending immiscible components across all skin types.

Related

Similar Ingredients

Finding similar ingredients…