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PEG-75 LANOLIN OIL.

Valuable CAS 68648-38-4 / SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

PEG-75 Lanolin Oil is a highly versatile, ethoxylated derivative of lanolin, prized for its multi-functional role as an emollient, emulsifier, and humectant. It effectively enhances skin hydration and softness while contributing to the stability and texture of cosmetic formulations.

Summary

Emollient Emulsifying Surfactant Humectant Hair Conditioning Rheology Modifier Cleansing Solubilizer

Science

Mechanism of Action

On the skin, PEG-75 Lanolin functions as an emollient by establishing a protective barrier that reduces transepidermal water loss, thereby maintaining the skin's softness, smoothness, and suppleness. It also acts as a lubricant, imparting a smooth feel to the skin's surface. In formulations, it serves as a surfactant and emulsifier, reducing surface tension to facilitate the stable combination of oil and water phases, particularly in oil-in-water emulsions. Furthermore, it acts as a solubilizer, enabling the integration of hydrophobic substances like essential oils and fragrances into aqueous solutions to form clear mixtures. Its humectant properties attract and retain moisture, while also acting as a hair conditioning agent, a rheology modifier to influence product viscosity, and a mild cleansing agent.

Research

Clinical Evidence

High confidence
Effective range 0.5–20%
Optimal

20%

Key findings

  1. 01 This concentration range is recommended for effective use in skin and hair products, with levels exceeding 20% potentially leading to minor adverse reactions such as rashes, itching, or redness.
  2. 02 A comprehensive review of PEG Lanolins, including PEG-75 Lanolin, indicated these ingredients are non-irritating and non-sensitizing in human patient studies within this broad concentration range.
  3. 03 Patch tests conducted on 11 human subjects over a four-week period demonstrated no adverse skin reactions, confirming excellent skin tolerance at full concentration.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 2 – 10
0 7 14

Stability

PEG-75 Lanolin exhibits robust stability within a wide pH range of 2.0 to 10.0, maintaining clarity in both aqueous and ethanolic solutions. For integration into formulations, it can be melted with the oil phase or dissolved directly into the aqueous phase. Prolonged exposure to temperatures exceeding 80 °C should be avoided to preserve its integrity.

Safety

Safety Profile

CIR Status
Safe as used
Max tested
20%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has affirmed PEG-75 Lanolin, along with other PEG Lanolin ingredients, as safe for use in cosmetics and personal care products. It is generally regarded as non-comedogenic and typically causes minimal to no skin or eye irritation. While studies demonstrate mild or negligible irritation at high concentrations (e.g., 50-100% for eye irritation), concentrations above 20% may, in some individuals, lead to minor side effects such as rashes, itching, or redness. Allergic reactions are rare and primarily confined to individuals with pre-existing lanolin allergies. There is a potential for trace amounts of 1,4-dioxane, a by-product of the ethoxylation process, which can be mitigated through purification. Although one source suggests caution for use in formulations intended for children and pregnant women, this is not a universally enforced restriction.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

PEG-75 Lanolin Oil is a valuable, well-tolerated ingredient offering significant emollient, hydrating, and emulsifying benefits, making it suitable for a broad spectrum of skincare and hair care formulations.

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