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PEG-7 METHYL ETHER.

Valuable CAS 9004-74-4 / SOLVENT

PEG-7 Methyl Ether is a versatile polyglycol ether functioning as a solvent, humectant, and emulsifier to enhance formula stability and active ingredient distribution. It precisely binds water, delivering long-term hydration and mitigating moisture loss in the skin.

Summary

Solvent Humectant Emulsifier Solubilizer Surfactant Skin Conditioning Agent Consistency Enhancer Binding Agent Softening Agent Fixative

Science

Mechanism of Action

This ingredient demonstrates a multifaceted mechanism within skincare formulations. As a potent solvent, it efficiently dissolves various substances, facilitating the uniform dispersion and enhanced percutaneous delivery of active compounds. Its humectant capacity is driven by the formation of hydrogen bonds with water molecules, thereby retaining moisture within the stratum corneum and demonstrably reducing transepidermal water evaporation for sustained hydration. Furthermore, it acts as an emulsifier and solubilizer, critically enabling the stable integration of immiscible oil and water phases, preventing product separation. It also functions as a surfactant, assisting in the gentle removal of epidermal debris and oils, and is recognized for its skin conditioning properties.

Research

Clinical Evidence

Insufficient-data confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Polyethylene Glycol Monomethyl Ether exhibits robust chemical and thermal stability, maintaining integrity across a wide range of pH levels, including high acidity and alkalinity, and elevated temperatures. Its non-ionic nature ensures insensitivity to electrolytes in aqueous solutions, contributing to exceptional formulation stability.

Conflicts

  • Final formulations must be meticulously developed to ensure non-irritating properties.
  • Application is not recommended on skin that is damaged or compromised.
  • Manufacturers are mandated to ensure the scrupulous removal of manufacturing impurities and by-products, specifically ethylene oxide and 1,4-dioxane.

Safety

Safety Profile

CIR Status
Safe with restrictions
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) Expert Panel has concluded that alkyl polyethylene glycol (PEG) ethers, including PEG-7 Methyl Ether, are deemed safe for use in cosmetic applications when formulated to be non-irritating. While a specific maximum safe concentration has not been established, its safety profile is contingent upon the final formulation demonstrating no irritant potential. Animal studies indicated slight to moderate erythema and desquamation at concentrations up to 50% solution or ≤5000 mg/kg; however, these observations were not classified as toxicologically significant within the broader safety assessment.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

PEG-7 Methyl Ether is a valuable multifunctional ingredient, enhancing product stability, ingredient delivery, and skin hydration, provided it is precisely formulated to be non-irritating and free from synthesis impurities.

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