Science
Mechanism of Action
PEG-66 TRIHYDROXYSTEARIN operates as a dual-action ingredient, providing both cleansing and emulsifying properties. The trihydroxystearin portion conditions the skin, serving as a solvent and a nonaqueous viscosity-increasing agent to hydrate and soften the skin, improve its texture, and contribute to a protective barrier that reduces trans-epidermal water loss. As a polyethylene glycol (PEG) derivative, it additionally offers surfactant and humectant benefits, potentially enhancing ingredient penetration and attracting moisture through hydrogen bonding with water molecules.
Research
Clinical Evidence
Low confidenceN/A
Key findings
- 01 The non-PEG version, Trihydroxystearin, is effectively utilized as an emollient and thickening agent in cosmetic applications, typically at concentrations ranging from 1% to 7%.
- 02 Broader clinical studies on PEG Stearates, at concentrations up to 25%, have demonstrated that these compounds are non-irritating and non-sensitizing.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The non-PEG Trihydroxystearin component is stable at a pH of 7.0 but can undergo hydrolysis in the presence of strong acids or alkalis. For optimal formulation, Trihydroxystearin is recommended to be incorporated into the heated oil phase, specifically between 55-65°C (130-140°F), with high shear mixing for 10-20 minutes. Continuous stirring should be maintained during the cool-down phase until the mixture reaches below 45°C (100°F) to prevent graininess. The presence of higher polarity oils or solvents may necessitate a lower upper temperature limit for incorporation.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has deemed PEG Stearates, a category encompassing PEG-66 TRIHYDROXYSTEARIN, safe for use in cosmetics under current practices of concentration. The panel has also revised its stance, removing previous concerns regarding the use of PEGs on damaged skin. While a specific maximum concentration for PEG-66 TRIHYDROXYSTEARIN is not explicitly stated, other PEG Stearates are reported in uses up to 10.1%, and non-PEG Trihydroxystearin is considered well-tolerated with a low risk of irritation or allergic reactions.
Your Skin
Skin Compatibility
Our Assessment
Verdict
PEG-66 TRIHYDROXYSTEARIN is a valuable multi-functional ingredient, effectively acting as an emulsifier, cleansing agent, and skin conditioner with a favorable safety profile across all skin types.
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