Science
Mechanism of Action
This ingredient operates by significantly reducing interfacial tension between immiscible liquids, acting as an emulsifier to create stable oil-in-water systems. As a solubilizer, it effectively integrates oil-soluble compounds into aqueous solutions. It functions as a mild, non-ionic surfactant, gently lifting dirt, excess oil, and impurities from the skin without stripping essential moisture. Furthermore, it provides skin-replenishing fatty acids, enhancing the skin's surface barrier to prevent transepidermal water loss and promote hydration.
Research
Clinical Evidence
Medium confidence4%
Key findings
- 01 Effective as an emulsifier, emollient, refatting agent, solubilizer, and wetting agent in cosmetic formulations at concentrations between 0.5% and 5%.
- 02 Demonstrated good makeup removal efficacies against challenging substances like oily marker pen and lip fluid in in vivo studies, with effective concentrations noted between 4% and 8%. It's important to note that the established maximum concentration for safety in formulations is 5%.
- 03 Aqueous solutions up to 5% and formulations containing 4% were found to be non-ocular irritants in rabbit studies, providing evidence for its safety when properly formulated.
Transparency
Dusting Analysis
No data suggests that PEG-6 Caprylic/Capric Glycerides is commonly 'dusted' or used below effective concentrations to mislead consumers.
The Formula
Formulation
Stability
This ingredient exhibits good stability in electrolyte solutions and is resistant to hard water. It is stable under low pH conditions but susceptible to hydrolysis at high pH. It can be incorporated into formulations via hot or cold processes, typically added to the water phase. For optimal solubilization of oils, it is recommended to pre-mix PEG-6 Caprylic/Capric Glycerides with the oil phase before integration into the main formulation.
Safety
Safety Profile
The CIR Expert Panel has determined PEGylated alkyl glycerides, including PEG-6 Caprylic/Capric Glycerides, to be safe for use in cosmetics at current concentrations and practices, provided the final formulation is non-irritating. While the undiluted form can be a strong ocular irritant, solutions up to 5% and formulations containing 4% have been shown to be non-irritating to the eyes in studies. It contains minimal levels of 1,4-dioxane (≤5 ppm) and ethylene oxide (≤1 ppm) and complies with regulatory limits for agricultural pesticides. Approved by the FDA for use in cosmetics, it is broadly considered non-irritating and non-sensitizing when incorporated into products as intended for skin application.
Your Skin
Skin Compatibility
Our Assessment
Verdict
PEG-6 Caprylic/Capric Glycerides is a valuable, multifunctional ingredient, offering effective yet gentle cleansing, solubilizing, and skin-conditioning benefits, making it suitable for a wide array of skin types and product formulations.
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